HepPar-1
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HepPar-1 is an commonly used immunostain.
Positive
- Hepatocellular carcinoma - 18/19 cases.[1]
Occasionally positive
- Gastric adenocarcinoma.
- Lung adenocarcinoma - especially SMARCA4-deficient non-small cell carcinoma of the lung.[2]
See also
References
- ↑ Fan, Z.; van de Rijn, M.; Montgomery, K.; Rouse, RV. (Feb 2003). "Hep par 1 antibody stain for the differential diagnosis of hepatocellular carcinoma: 676 tumors tested using tissue microarrays and conventional tissue sections.". Mod Pathol 16 (2): 137-44. doi:10.1097/01.MP.0000052103.13730.20. PMID 12591966.
- ↑ Agaimy, A.; Fuchs, F.; Moskalev, EA.; Sirbu, H.; Hartmann, A.; Haller, F. (Nov 2017). "SMARCA4-deficient pulmonary adenocarcinoma: clinicopathological, immunohistochemical, and molecular characteristics of a novel aggressive neoplasm with a consistent TTF1". Virchows Arch 471 (5): 599-609. doi:10.1007/s00428-017-2148-5. PMID 28555282.