Nuclear pleomorphism

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Extreme nuclear pleomorphism in a case of glioblastoma.

Nuclear pleomorphism is a common finding in malignant lesions. Anisonucleosis is often used as a synonym for nuclear pleomorphism; iso- means equal or identical,[1] and an- means not.[2]

Definition

Nuclear pleomorphism is the marked variation of:[3]

  1. Nuclear size.
  2. Nuclear shape.
  3. Nuclear staining (especially with hyperchromasia).

Memory device 3 S: size, shape, staining.

Images

See also

References

  1. URL: http://dictionary.reference.com/browse/iso-?s=ts. Accessed on: 26 September 2013.
  2. URL: http://dictionary.reference.com/browse/an-?s=t. Accessed on: 26 September 2013.
  3. Rashid, F.; Ul Haque, A. (Dec 2011). "Frequencies of different nuclear morphological features in prostate adenocarcinoma.". Ann Diagn Pathol 15 (6): 414-21. doi:10.1016/j.anndiagpath.2011.06.002. PMID 21849255.