Systemic lupus erythematosus lymphadenopathy
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Systemic lupus erythematosus lymphadenopathy is a very rare lymph node pathology seen in systemic lupus erythematosus.
| Systemic lupus erythematosus lymphadenopathy | |
|---|---|
| Diagnosis in short | |
 Systemic lupus erythematosus lymphadenopathy. H&E stain. | |
|
| |
| LM | lymph node with necrosis, hematoxylin bodies (in necrotic foci) |
| LM DDx | Kikuchi disease |
| Site | lymph node - see lymph node pathology |
|
| |
| Associated Dx | systemic lupus erythematosus |
| Clinical history | +/-hx of systemic lupus erythematosus |
| Signs | see systemic lupus erythematosus |
| Symptoms | see systemic lupus erythematosus |
| Prevalence | uncommon |
| Blood work | see systemic lupus erythematosus |
| Clin. DDx | lymphoma, other causes of lymphadenopathy |
| Treatment | treatment for SLE |
General
- Lymphadenopathy associated with systemic lupus erythematosus (SLE).
- Lymphadenopathy may be the first presentation of SLE.[1]
Clinical DDx:
Microscopic
Features:[2]
- Necrosis.
- Hematoxylin bodies (in necrotic foci).
- Dark blue irregular bodies on H&E.
DDx:
Images
SLE lymphadenopathy - intermed. mag. (WC)
SLE lymphadenopathy - high mag. (WC)
SLE lymphadenopathy - very high mag. (WC)
See also
References
- ↑ Smith, LW.; Petri, M. (Oct 2013). "Diffuse lymphadenopathy as the presenting manifestation of systemic lupus erythematosus.". J Clin Rheumatol 19 (7): 397-9. doi:10.1097/RHU.0b013e3182a6a924. PMID 24048114.
- ↑ Kojima, M.; Nakamura, S.; Itoh, H.; Yoshida, K.; Asano, S.; Yamane, N.; Komatsumoto, S.; Ban, S. et al. (1997). "Systemic lupus erythematosus (SLE) lymphadenopathy presenting with histopathologic features of Castleman' disease: a clinicopathologic study of five cases.". Pathol Res Pract 193 (8): 565-71. PMID 9406250.