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Difference between revisions of "Invasive breast cancer"
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→Other: mv
(→Sentinel lymph node biopsy: more) |
(→Other: mv) |
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Some hospitals use: | Some hospitals use: | ||
*CAM5.2 (LMWK) - to look for isolated tumour cells and small lymph node metstases. | *CAM5.2 (LMWK) - to look for isolated tumour cells and small lymph node metstases. | ||
==Trivia== | ==Trivia== | ||
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===Natural history=== | ===Natural history=== | ||
There is a theory that up to 22% of small (radiographically detected) breast tumours regress, based on an analysis in a large population.<ref name=pmid19029493>{{Cite journal | last1 = Zahl | first1 = PH. | last2 = Maehlen | first2 = J. | last3 = Welch | first3 = HG. | title = The natural history of invasive breast cancers detected by screening mammography. | journal = Arch Intern Med | volume = 168 | issue = 21 | pages = 2311-6 | month = Nov | year = 2008 | doi = 10.1001/archinte.168.21.2311 | PMID = 19029493 }}</ref> The study is supported by NCI's SEER data.<ref name=pmid19468099>{{Cite journal | last1 = Jatoi | first1 = I. | last2 = Anderson | first2 = WF. | title = Breast cancer overdiagnosis with screening mammography. | journal = Arch Intern Med | volume = 169 | issue = 10 | pages = 999-1000, author reply 1000-1 | month = May | year = 2009 | doi = 10.1001/archinternmed.2009.95 | PMID = 19468099 }}</ref> Also, it generated many comments.<ref name=pmid19029493/> | There is a theory that up to 22% of small (radiographically detected) breast tumours regress, based on an analysis in a large population.<ref name=pmid19029493>{{Cite journal | last1 = Zahl | first1 = PH. | last2 = Maehlen | first2 = J. | last3 = Welch | first3 = HG. | title = The natural history of invasive breast cancers detected by screening mammography. | journal = Arch Intern Med | volume = 168 | issue = 21 | pages = 2311-6 | month = Nov | year = 2008 | doi = 10.1001/archinte.168.21.2311 | PMID = 19029493 }}</ref> The study is supported by NCI's SEER data.<ref name=pmid19468099>{{Cite journal | last1 = Jatoi | first1 = I. | last2 = Anderson | first2 = WF. | title = Breast cancer overdiagnosis with screening mammography. | journal = Arch Intern Med | volume = 169 | issue = 10 | pages = 999-1000, author reply 1000-1 | month = May | year = 2009 | doi = 10.1001/archinternmed.2009.95 | PMID = 19468099 }}</ref> Also, it generated many comments.<ref name=pmid19029493/> | ||
===Missed macrometastases=== | |||
The effect of missed macrometastases is small; this implies using [[IHC]] to look for isolated tumour cells is money that isn't well spent.<ref name=pmid21247310>PMID 21247310.</ref> | |||
=See also= | =See also= | ||