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Difference between revisions of "Dermatologic neoplasms"
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→Eccrine poroma: +trichoepithelioma
(→Eccrine carcinoma: +image) |
(→Eccrine poroma: +trichoepithelioma) |
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| Line 210: | Line 210: | ||
Notes: | Notes: | ||
*Area above gland appears crusted. | *Area above gland appears crusted. | ||
==Trichoepithelioma== | |||
===General=== | |||
*Benign. | |||
**Maligant counterpart of trichoepithelioma: [[trichilemmal carcinoma]]. | |||
*May be familial: | |||
**Multiple familial trichoepithelioma.<ref name=pmid15289313>{{Cite journal | last1 = Salhi | first1 = A. | last2 = Bornholdt | first2 = D. | last3 = Oeffner | first3 = F. | last4 = Malik | first4 = S. | last5 = Heid | first5 = E. | last6 = Happle | first6 = R. | last7 = Grzeschik | first7 = KH. | title = Multiple familial trichoepithelioma caused by mutations in the cylindromatosis tumor suppressor gene. | journal = Cancer Res | volume = 64 | issue = 15 | pages = 5113-7 | month = Aug | year = 2004 | doi = 10.1158/0008-5472.CAN-04-0307 | PMID = 15289313 }}</ref> | |||
**Brooke-Spiegler syndrome. | |||
===Microscopic=== | |||
Features:<ref>URL: [http://emedicine.medscape.com/article/1060049-workup#a0723 http://emedicine.medscape.com/article/1060049-workup#a0723]. Accessed on: 31 August 2011.</ref> | |||
*Well-circumscribed cell nest in the superficial dermis. | |||
*Surrounding by a fibrous stroma. | |||
*Basaloid cells with [[peripheral pallisading]]. | |||
*+/-Surround keratin-filled cysts. | |||
*Fibroblasts-like cell aggregate, similar to a follicular papillae (papillary-mesenchymal body). | |||
Notes: | |||
*Very rarely an artifical cleft - as in [[basal cell carcinoma]]. | |||
Variants: | |||
*Desmoplastic. | |||
DDx: | |||
*[[Basal cell carcinoma]]. | |||
==Kaposi sarcoma== | ==Kaposi sarcoma== | ||