Trichilemmal carcinoma

Trichilemmal carcinoma is a rare malignant skin tumour.

General

• Super rare.
• Not well-described.

Microscopic

Features:

• Clear (glycogen-rich) cytoplasm in center of lesion.
• Peripheral palisading at edge of lesion - root sheath differentiation (hair follicle).
• Contiguous with hair follicle or assoc. with trichilemmoma.

DDx:

• Squamous cell carcinoma, clear cell variant.
• Basal cell carcinoma, clear cell variant.
• Trichilemmoma.

See also

• Dermatologic neoplasms.