Difference between revisions of "Foamy gland carcinoma"

From Libre Pathology
Jump to navigation Jump to search
Line 15: Line 15:
Note:
Note:
*Prominent [[nucleoli]] usually infrequent ''or'' absent!<ref name=pmid19033862/>
*Prominent [[nucleoli]] usually infrequent ''or'' absent!<ref name=pmid19033862/>
*Can be thought of as [[pseudohyperplastic adenocarcinoma]] without the nucleoli.


DDx:
DDx:

Revision as of 02:06, 23 October 2014

Foamy gland carcinoma, also foamy gland adenocarcinoma,[1] is an uncommon variant of prostate carcinoma that has a bland appearance and may be confused with benign glands.

General

  • Rare.
  • Usually low grade, i.e. Gleason score 6/10.[1]

Microscopic

Features:

  • Increased glandular density - key feature.
  • Eosinophilic intraluminal amorphous secretions - key feature.
  • Abundant foamy cytoplasm.
  • Tufted glandular border.
  • Gland size larger than "typical" prostate cancer.

Note:

DDx:

Images

  • Intraluminal eosinophilic crystalloid in foamy glands. (WC)

www:

See also

References

  1. ↑ 1.0 1.1 1.2 Zhao, J.; Epstein, JI. (Apr 2009). "High-grade foamy gland prostatic adenocarcinoma on biopsy or transurethral resection: a morphologic study of 55 cases.". Am J Surg Pathol 33 (4): 583-90. doi:10.1097/PAS.0b013e31818a5c6c. PMID 19033862.
Retrieved from "https://librepathology.org/w/index.php?title=Foamy_gland_carcinoma&oldid=34352"