Difference between revisions of "Drug toxicity"
Jump to navigation
Jump to search
(+PPI) |
|||
| Line 16: | Line 16: | ||
Image:Cecal_adenocarcinoma.jpg | Kayexalate crystals and adenocarcinoma. (WC) | Image:Cecal_adenocarcinoma.jpg | Kayexalate crystals and adenocarcinoma. (WC) | ||
</gallery> | </gallery> | ||
==Proton pump inhibitor== | |||
{{Main|Proton pump inhibitor effect}} | |||
==See also== | ==See also== | ||
Revision as of 17:49, 10 January 2014
Drug toxicity, also drug reaction, in pathology is often a diagnosis of exclusion. Few drugs leave a distinctive histomorphologic pattern.
This article covers a few of the distinctive histomorphologic pattern and links to other articles that deal with specific organ systems.
Sodium polystyrene sulfonate
- AKA Kayexalate (trade name).
General
- Used to treat hyperkalemia.
Microscopic
Features:[1]
- Purple blobs on H&E stain - look somewhat like calcium phosphate.
- Can cause focal necrosis.
Image
Kayexalate crystals and adenocarcinoma. (WC)
Proton pump inhibitor
Main article: Proton pump inhibitor effect
See also
References
- ↑ Abraham SC, Bhagavan BS, Lee LA, Rashid A, Wu TT (May 2001). "Upper gastrointestinal tract injury in patients receiving kayexalate (sodium polystyrene sulfonate) in sorbitol: clinical, endoscopic, and histopathologic findings". Am. J. Surg. Pathol. 25 (5): 637-44. PMID 11342776. http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0147-5185&volume=25&issue=5&spage=637.