Difference between revisions of "Sudden infant death syndrome"
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'''Sudden infant death syndrome''', abbreviated '''SIDS''', is an unexplained rapid (and unexpected) death of a person less than one year old, that is ''not'' explained after a full [[autopsy]], correlations with the death scene and the (clinical) history.<ref name=Ref_PCPBOD8_251>{{Ref PCPBoD8|251}}</ref> | '''Sudden infant death syndrome''', abbreviated '''SIDS''', is an unexplained rapid (and unexpected) death of a person older than one month and less than one year old, that is ''not'' explained after a full [[autopsy]], correlations with the death scene and the (clinical) history.<ref name=Ref_PCPBOD8_251>{{Ref PCPBoD8|251}}</ref><ref name=pmid22110293/> | ||
==Pathogenesis== | ==Pathogenesis== | ||
Revision as of 01:09, 20 April 2012
Sudden infant death syndrome, abbreviated SIDS, is an unexplained rapid (and unexpected) death of a person older than one month and less than one year old, that is not explained after a full autopsy, correlations with the death scene and the (clinical) history.[1][2]
Pathogenesis
It is not understood. One hypothesis for SIDS is: immaturity of the arcuate nucleus of medulla (which control respiratory frequency).[1]
Risk factors
Parent:
- Low socioeconomic status.
- Maternal substance use.[2]
Child:[2]
- Male.[3]
- Prematurity.
- Low birth weight.
- IUGR.
- Prone sleep, i.e. put to sleep on the front.
- Soft bed mattress.
Note:
- Breast feeding reduces the risk.[4]
Diagnosis
- Diagnosis of exclusions with:[5]
- Negative autopsy.
- No significant pathology that could explain death.
- Negative autopsy.
DDx:
- Overlay (positional asphyxia).
- Suffocation.[6]
- Hypertrophic cardiomyopathy.
- Channelopathy.[5]
See also
References
- ↑ 1.0 1.1 Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 251. ISBN 978-1416054542.
- ↑ 2.0 2.1 2.2 Athanasakis, E.; Karavasiliadou, S.; Styliadis, I. (Apr 2011). "The factors contributing to the risk of sudden infant death syndrome.". Hippokratia 15 (2): 127-31. PMC 3209674. PMID 22110293. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209674/.
- ↑ Trachtenberg, FL.; Haas, EA.; Kinney, HC.; Stanley, C.; Krous, HF. (Apr 2012). "Risk Factor Changes for Sudden Infant Death Syndrome After Initiation of Back-to-Sleep Campaign.". Pediatrics 129 (4): 630-8. doi:10.1542/peds.2011-1419. PMID 22451703.
- ↑ Zotter, H.; Pichler, G. (Feb 2012). "Breast feeding is associated with decreased risk of sudden infant death syndrome.". Evid Based Med. doi:10.1136/ebmed-2011-100337. PMID 22345043.
- ↑ 5.0 5.1 Brion, M.; Allegue, C.; Santori, M.; Gil, R.; Blanco-Verea, A.; Haas, C.; Bartsch, C.; Poster, S. et al. (Feb 2012). "Sarcomeric gene mutations in sudden infant death syndrome (SIDS).". Forensic Sci Int. doi:10.1016/j.forsciint.2012.01.018. PMID 22361390.
- ↑ Gilbert, NL.; Fell, DB.; Joseph, KS.; Liu, S.; León, JA.; Sauve, R.; Kramer, M.; Shah, P. et al. (Mar 2012). "Temporal trends in sudden infant death syndrome in Canada from 1991 to 2005: contribution of changes in cause of death assignment practices and in maternal and infant characteristics.". Paediatr Perinat Epidemiol 26 (2): 124-30. doi:10.1111/j.1365-3016.2011.01248.x. PMID 22324498.