Difference between revisions of "Basics"

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*Subcapsular space - the first place to look for mets.
*Subcapsular space - the first place to look for mets.
*Lymph node metstasis are usually obvious.
*Lymph node metstasis are usually obvious.
*Histiocytes may be difficult to separate from tumour - esp. initially.
*Histiocytes may be difficult to separate from tumour - especially initially.
**Histiocytes usually are in germinal centre, i.e. the node architecture helps,
**Histiocytes (usually) are in germinal centres, i.e. the node architecture helps.
**Malignant cells have to have malignant features, i.e. the NC ratio is abnormal, there is [[nuclear pleomorphism]].
**Malignant cells, generally, have to have malignant features, i.e. the NC ratio is abnormal, there is [[nuclear pleomorphism]].


See: ''[[Lymph node]]'' article for a detailed description of cell types in a lymph node.
See: ''[[Lymph node]]'' article for a detailed description of cell types in a lymph node.
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