Difference between revisions of "Adenocarcinoma"
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[[Image:Colorectal adenocarcinoma cytology low mag.jpg|thumb|right|250px|Cytologic preparation showing an adenocarcinoma.]] | |||
'''Adenocarcinoma''' is a form of [[cancer]] that arises from glandular tissue. Adenocarcinoma can arise in many sites. | '''Adenocarcinoma''' is a form of [[cancer]] that arises from glandular tissue. Adenocarcinoma can arise in many sites. | ||
Revision as of 02:26, 23 October 2014
Adenocarcinoma is a form of cancer that arises from glandular tissue. Adenocarcinoma can arise in many sites.
Adenocarcinoma not otherwise specified, also adenocarcinoma NOS, is a non-specific malignant diagnosis that without further information is not very useful for treatment decisions.
Types of adenocarcinoma
Site specific
Gastrointestinal pathology
Esophagus
Stomach
Duodenum
Ampulla of Vater
Pancreas
Gallbladder
Colon and rectum
Other
Lung
Salivary gland
Gynecologic pathology
Ovary
Endometrium
Cervix
- Endocervical adenocarcinoma.
- Villoglandular adenocarcinoma of the cervix.
- Minimal deviation adenocarcinoma of the uterine cervix.
Genitourinary pathology
Prostate
- Prostatic adenocarcinoma, not otherwise specified.
- Prostatic ductal adenocarcinoma.
- PIN-like prostatic ductal adenocarcinoma.
Testis
Urinary bladder
General type
Microscopic (generic)
Features:
- Gland forming - round/ovoid/tubular spaces.
- Eccentric nucleus.
- Moderate cytoplasm +/- vacuoles.
- +/-Prominent nucleolus.
- +/-Nuclear atypia - dependent on type/site.
DDx:
- Carcinoma (poorly differentiated).
- Sarcoma, esp. epithelioid sarcomas.
- Benign glands.
Grading
Adenocarcinomas are often graded by their glandular component:[1]
- Grade 1: >95% of tumour glandular.
- Grade 2: 50-95% of tumour glandular.
- Grade 3: <50% of tumour glandular.
See also
References
- ↑ URL: http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/Esophagus_11protocol.pdf. Accessed on: 6 April 2012.