Difference between revisions of "Inflammatory bowel disease"

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COLON (SITE NOT FURTHER SPECIFIED), BIOPSIES:
COLON (SITE NOT FURTHER SPECIFIED), BIOPSIES:
- COLORECTAL-TYPE MUCOSA WITH PANETH CELLS, FOCAL CRYPTITIS AND CRYPT ABSCESSES, SEE COMMENT.
- MODERATE CHRONIC ACTIVE COLITIS.
- FOCALLY ABUNDANT EOSINOPHILS.
- NEGATIVE FOR DYSPLASIA.
- NEGATIVE FOR DYSPLASIA.
- PLEASE SEE COMMENT.


COMMENT:
COMMENT:
The sections show colorectal-type mucosa with focal cryptitis and rare neutrophilic crypt
abscesses.  There are up to 80 eosinophils per high power field (HPF), where one HPF is
~0.2376 mm*mm.  No eosinophilic crypt abscesses are identified.  Paneth cells are
present focally; however, the significance of the paneth cells cannot determined as the
biopsy sites are not known.
Mild architectural changes, suggestive of a chronic colitis, are present. No granulomas are
Mild architectural changes, suggestive of a chronic colitis, are present. No granulomas are
identified. Lymphoid aggregates with germinal centre formation are present in multiple
identified. Lymphoid aggregates with germinal centre formation are present in multiple
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The lamina propria has abundant plasma cells throughout the fragments; no fragments have
The lamina propria has abundant plasma cells throughout the fragments; no fragments have
apparent relative sparing.  
apparent relative sparing. It is not possible to assess whether there is a mild gradient
 
of less severe to more severe architectural changes from proximal to distal large bowel, as
It is not possible to assess whether there is a mild gradient of less severe to more  
may be seen in individuals with ulcerative colitis.
severe architectural changes from proximal to distal large bowel, as may be seen in  
individuals with ulcerative colitis. The significance of the paneth cells cannot
determined as the biopsy sites are not known.


The findings are compatible with inflammatory bowel disease and chronic active infectious
The findings are compatible with inflammatory bowel disease and chronic active infectious
colitides.
colitides. Clinical correlation is suggested.
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