Irritable bowel syndrome
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Irritable bowel syndrome, abbreviated IBS, is a diagnosis exclusion that is considered to have no histopathologic abnormalities on routine histologic examination.[1]
General
- Clinical diagnosis - different criteria exist Manning and Rome.[2]
- Fecal calprotectin negative.[3]
Microscopic
Features:
- No abnormalities - see normal colon.
DDx - subtle pathologies:
Note:
- No significant association with other endoscopically subtle pathology, e.g. melanosis coli and microscopic colitis, when clinical criteria are fulfilled.[2]
See also
References
- ↑ Kirsch R, Kirsch RH, Riddell RH, Riddell R (December 2006). "Histopathological alterations in irritable bowel syndrome". Mod. Pathol. 19 (12): 1638–45. doi:10.1038/modpathol.3800704. PMID 17013373. http://www.nature.com/modpathol/journal/v19/n12/full/3800704a.html.
- ↑ 2.0 2.1 MacIntosh, DG.; Thompson, WG.; Patel, DG.; Barr, R.; Guindi, M. (Oct 1992). "Is rectal biopsy necessary in irritable bowel syndrome?". Am J Gastroenterol 87 (10): 1407-9. PMID 1415096.
- ↑ Nemakayala, DR.; Cash, BD. (Jan 2019). "Excluding irritable bowel syndrome in the inflammatory bowel disease patient: how far to go?". Curr Opin Gastroenterol 35 (1): 58-62. doi:10.1097/MOG.0000000000000493. PMID 30407259.
- ↑ Walker MM, Talley NJ, Inganäs L, Engstrand L, Jones MP, Nyhlin H, Agréus L, Kjellstrom L, Öst Å, Andreasson A (February 2015). "Colonic spirochetosis is associated with colonic eosinophilia and irritable bowel syndrome in a general population in Sweden". Hum Pathol 46 (2): 277–83. doi:10.1016/j.humpath.2014.10.026. PMID 25540866.