Difference between revisions of "Worst pattern of invasion"

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==General==
==General==
*WPOI is predictive of disease free survival in oral cancer.<ref name=pmid29672550/>
*WPOI is predictive of disease free survival in oral cancer.<ref name=pmid29672550/>
 
*WPOI five patterns - but generally divided into two (prognostic) groups:
WPOI is generally divided into two groups:
**WPOI 1-4: better prognosis.
*WPOI 1-4: better prognosis.
**WPOI 5: poor prognosis.
*WPOI 5: poor prognosis.


==Definition of WPOI 5==
==Definition of WPOI 5==

Revision as of 19:59, 18 October 2023

Worst pattern of invasion, abbreviated WPOI, is schema for classifying tumour morphologic patterns with the goal of predicting tumour behaviour.[1]

General

  • WPOI is predictive of disease free survival in oral cancer.[1]
  • WPOI five patterns - but generally divided into two (prognostic) groups:
    • WPOI 1-4: better prognosis.
    • WPOI 5: poor prognosis.

Definition of WPOI 5

WPOI 5 is defined as: >=1 mm normal tissue between two tumour masses.[2]

See also

References

  1. Jump up to: 1.0 1.1 Shimizu S, Miyazaki A, Sonoda T, Koike K, Ogi K, Kobayashi JI, Kaneko T, Igarashi T, Ueda M, Dehari H, Miyakawa A, Hasegawa T, Hiratsuka H (2018). "Tumor budding is an independent prognostic marker in early stage oral squamous cell carcinoma: With special reference to the mode of invasion and worst pattern of invasion". PLoS One 13 (4): e0195451. doi:10.1371/journal.pone.0195451. PMC 5909609. PMID 29672550. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909609/.
  2. Sinha N, Rigby MH, McNeil ML, Taylor SM, Trites JR, Hart RD, Bullock MJ (May 2018). "The histologic risk model is a useful and inexpensive tool to assess risk of recurrence and death in stage I or II squamous cell carcinoma of tongue and floor of mouth". Mod Pathol 31 (5): 772–779. doi:10.1038/modpathol.2017.183. PMID 29393297.