Difference between revisions of "Sudden natural death"

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'''Natural death''' happens.  It must be differentiated from other ways of dying (suicide, homicide, accidental).
'''Sudden natural death''' happens.  It must be differentiated from other ways of dying (suicide, homicide, accidental).


A list:<ref>http://www.ncbi.nlm.nih.gov/pubmed/16410164 http://www.ncbi.nlm.nih.gov/pubmed/17952460</ref>
==By system==
Respiratory:
===Respiratory<ref name=pmid16410164>{{cite journal |author=de la Grandmaison GL |title=Is there progress in the autopsy diagnosis of sudden unexpected death in adults? |journal=Forensic Sci. Int. |volume=156 |issue=2-3 |pages=138–44 |year=2006 |month=January |pmid=16410164 |doi=10.1016/j.forsciint.2004.12.024 |url=}}</ref>===
*Anaphylaxis.  
*[[Anaphylaxis]].  
*Asthma.
*[[Asthma]].
*Pulmonary embolism.
*[[Pulmonary embolism]].


Hemorrhagic:
===Cerebral===
*Ruptured AAA.
*[[SUDEP]] (sudden unexpected death in [[epilepsy]]).
*Peptic ulcer.  
 
*Cerebral aneurysm.
===Sudden cardiac death===
====Older====
*[[Atherosclerotic heart disease]] (ASHD); [[AKA]] coronary artery disease (CAD).  
*[[Hypertensive heart disease]] - a heart > ~400 g is considered good enough if nothing else is present.<ref>MSP. 29 September 2010.</ref>


Cerebral:
====Younger====
*SUDEP (sudden unexpected death in epilepsy).
*[[Arrhythmogenic right ventricular cardiomyopathy]].
*[[Hypertrophic cardiomyopathy]], e.g. [[hypertrophic obstructive cardiomyopathy]] (HOCM).


Cardiac:  
Notes:
*CAD.  
*The mechanism is usually [[cardiac arrhythmia|arrhythmia]].
*Right ventricular cardiomyopathy.
**Generally, this is usually not provable at [[autopsy]]; however, some findings have been proposed.<ref name=pmid15837088>{{Cite journal  | last1 = Baroldi | first1 = G. | last2 = Silver | first2 = MD. | last3 = Parolini | first3 = M. | last4 = Pomara | first4 = C. | last5 = Turillazzi | first5 = E. | last6 = Fineschi | first6 = V. | title = Myofiberbreak-up: a marker of ventricular fibrillation in sudden cardiac death. | journal = Int J Cardiol | volume = 100 | issue = 3 | pages = 435-41 | month = Apr | year = 2005 | doi = 10.1016/j.ijcard.2004.10.007 | PMID = 15837088 }}</ref>
*Arrhythmia.


Detailed cardiac:
====Detailed cardiac<ref name=pmid16410164/>====
*CAD, hypertrophic CM.
*[[ASHD]].
*ARVC.
*[[Cardiomyopathy]].
*DCM.
**[[Hypertrophic cardiomyopathy]].
*Lymphocytic myocarditis.  
**[[Arrhythmogenic right ventricular cardiomyopathy]] (ARVC).
*Floppy MV.
**[[Dilated cardiomyopathy]] (DCM).
*Aortic valve stenosis.
*[[Lymphocytic myocarditis]].  
*[[Floppy mitral valve]].
*[[Aortic valve stenosis]].
*Congenital cardiac abnormality.
*Congenital cardiac abnormality.
*Coronary artery dissection.  
*Coronary artery dissection.  
*Aortic dissection.
*[[Aortic dissection]].
*Arrhythmia.  
*[[Cardic arrhythmia|Arrhythmia]].<ref>URL: [http://www.sads.org.uk/causes_of_sads.htm http://www.sads.org.uk/causes_of_sads.htm]. Accessed on: 29 September 2010.</ref>
**Long QT syndrome, Brugada syndrome, short QT syndrome, catecholaminergic polymorphic VT, anomalous conduction pathways, dysplasia of nodal arteries, atrioventricular node tumour.
**Long QT syndrome.
**Brugada syndrome.
**Short QT syndrome.
**Catecholaminergic polymorphic ventricular tachycardia (CPVT).
**Anomalous conduction pathways.
**Dysplasia of nodal arteries.
**Atrioventricular node tumour.
**Sodium channel disease.
**Idiopathic ventricular fibrillation.
*Tumours.
**[[Cystic tumour of the atrioventricular nodal region]].
 
Post-mortem (molecular) testing for arrhythmias:<ref>MSP. 29 September 2010:</ref>
*CPVT.
*Sodium channel disease.
*Brugada syndrome.
 
==By mechanism==
===Hemorrhagic<ref name=pmid16410164/>===
*Ruptured AAA.
*Peptic ulcer.
*[[Cerebral aneurysm]].


==See also==
==See also==
*[[Forensic pathology]].
*[[Forensic pathology]].
*[[Channelopathies]].


==Reference==
==Reference==
{{reflist|1}}
{{reflist|2}}


[[Category:Autopsy]]
[[Category:Autopsy]]

Latest revision as of 05:18, 21 July 2016

Sudden natural death happens. It must be differentiated from other ways of dying (suicide, homicide, accidental).

By system

Respiratory[1]

Cerebral

Sudden cardiac death

Older

Younger

Notes:

  • The mechanism is usually arrhythmia.
    • Generally, this is usually not provable at autopsy; however, some findings have been proposed.[3]

Detailed cardiac[1]

Post-mortem (molecular) testing for arrhythmias:[5]

  • CPVT.
  • Sodium channel disease.
  • Brugada syndrome.

By mechanism

Hemorrhagic[1]

See also

Reference

  1. ↑ 1.0 1.1 1.2 de la Grandmaison GL (January 2006). "Is there progress in the autopsy diagnosis of sudden unexpected death in adults?". Forensic Sci. Int. 156 (2-3): 138–44. doi:10.1016/j.forsciint.2004.12.024. PMID 16410164.
  2. ↑ MSP. 29 September 2010.
  3. ↑ Baroldi, G.; Silver, MD.; Parolini, M.; Pomara, C.; Turillazzi, E.; Fineschi, V. (Apr 2005). "Myofiberbreak-up: a marker of ventricular fibrillation in sudden cardiac death.". Int J Cardiol 100 (3): 435-41. doi:10.1016/j.ijcard.2004.10.007. PMID 15837088.
  4. ↑ URL: http://www.sads.org.uk/causes_of_sads.htm. Accessed on: 29 September 2010.
  5. ↑ MSP. 29 September 2010:
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