49,256
edits
Difference between revisions of "Kimura disease"
Jump to navigation
Jump to search
→Microscopic
m (ALHE) |
|||
| (11 intermediate revisions by 2 users not shown) | |||
| Line 1: | Line 1: | ||
'''Kimura disease''' is a rare disease with abundant eosinophils. It may show-up in a [[lymph node]] specimen. It is similar to ''angiolymphoid hyperplasia with eosinophilia''.<ref>URL: [http://emedicine.medscape.com/article/1082603-overview http://emedicine.medscape.com/article/1082603-overview]. Accessed on: 14 January 2012.</ref> | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = Kimura_disease_-_very_high_mag.jpg | |||
| Width = | |||
| Caption = Kimura disease. [[H&E stain]]. | |||
| Micro = eosinophils and thick walled [[blood vessel]]s with [[hobnail]]ed endothelial cells | |||
| Subtypes = | |||
| LMDDx = [[angiolymphoid hyperplasia with eosinophilia]], [[drug reaction]], infection (parasitic), [[lymphoma]], [[LCH]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[lymph node]], head and neck | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = extremely rare | |||
| Bloodwork = eosinophilia | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = | |||
}} | |||
'''Kimura disease''' is a rare disease with abundant eosinophils. It may show-up in a [[lymph node]] specimen. It is similar to ''[[angiolymphoid hyperplasia with eosinophilia]]''.<ref>URL: [http://emedicine.medscape.com/article/1082603-overview http://emedicine.medscape.com/article/1082603-overview]. Accessed on: 14 January 2012.</ref> | |||
==General== | ==General== | ||
| Line 18: | Line 47: | ||
Features:<ref name=Ref_ILNP190>{{Ref ILNP|190}}</ref> | Features:<ref name=Ref_ILNP190>{{Ref ILNP|190}}</ref> | ||
*Angiolymphoid proliferation. | *Angiolymphoid proliferation. | ||
**Thick walled blood vessels with (plump) hobnail endothelial cells.<ref>URL: [http://emedicine.medscape.com/article/1098777-diagnosis http://emedicine.medscape.com/article/1098777-diagnosis]. Accessed on: 8 August 2010.</ref> | **Thick walled blood vessels with (plump) [[hobnail]] endothelial cells.<ref>URL: [http://emedicine.medscape.com/article/1098777-diagnosis http://emedicine.medscape.com/article/1098777-diagnosis]. Accessed on: 8 August 2010.</ref> | ||
*Eosinophils - abundant - '''key feature'''. | *Eosinophils - abundant - '''key feature'''. | ||
| Line 24: | Line 53: | ||
*Drug reaction. | *Drug reaction. | ||
*Parasitic infection. | *Parasitic infection. | ||
*[[Angiolymphoid hyperplasia with eosinophilia]]. | |||
Notes: | Notes: | ||
| Line 29: | Line 59: | ||
*Abundant eosinophils: consider [[Langerhans cell histiocytosis]]. | *Abundant eosinophils: consider [[Langerhans cell histiocytosis]]. | ||
Images | ===Images=== | ||
<gallery> | |||
Image:Kimura_disease_-_very_high_mag.jpg | Kimura disease - very high mag. (WC) | |||
Image:Kimura_disease_-_high_mag.jpg | Kimura disease - high mag. (WC) | |||
Image:Kimura_disease_-_intermed_mag.jpg | Kimura disease - intermed. mag. (WC) | |||
</gallery> | |||
==IHC== | ==IHC== | ||