Difference between revisions of "Epithelioid cell lesions"
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'''Epithelioid cell lesions''' are very common in pathology. | [[Image:Epithelioid sarcoma - cropped - very high mag.jpg|thumb|right|250px|An tumour with an epithelioid morphology ([[epithelioid sarcoma]]). [[H&E stain]].]] | ||
'''Epithelioid cell lesions''' are very common in pathology. Malignant epithelioid lesions are most often carcinomas... but may be a large number different tumours. | |||
==Classification== | |||
Broadly, epithelioid lesions are split into: | |||
*[[Small round cell tumours]]. | |||
*[[Large epithelioid tumours]]. | |||
A short | ==General differential diagnosis== | ||
A short DDx: | |||
*Carcinoma (primary and metastatic). | *Carcinoma (primary and metastatic). | ||
*[[Malignant melanoma]]. | *[[Malignant melanoma]]. | ||
*Sarcoma. | *Sarcoma. | ||
==Epithelioid sarcomas== | ===Epithelioid sarcomas=== | ||
All rules are made to be broken... some epithelioid lesions are sarcomas:<ref name=pmid19664495>{{cite journal |author=Dei Tos AP, Wagner AJ, Modena P, Comandone A, Leyvraz S |title=Epithelioid soft tissue tumors |journal=Semin. Oncol. |volume=36 |issue=4 |pages=347–57 |year=2009 |month=August |pmid=19664495 |doi=10.1053/j.seminoncol.2009.06.005 |url=}}</ref> | All rules are made to be broken... some epithelioid lesions are sarcomas:<ref name=pmid19664495>{{cite journal |author=Dei Tos AP, Wagner AJ, Modena P, Comandone A, Leyvraz S |title=Epithelioid soft tissue tumors |journal=Semin. Oncol. |volume=36 |issue=4 |pages=347–57 |year=2009 |month=August |pmid=19664495 |doi=10.1053/j.seminoncol.2009.06.005 |url=}}</ref> | ||
*[[Epithelioid sarcoma]]. | *[[Epithelioid sarcoma]]. | ||
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*[[Clear cell sarcoma]]. | *[[Clear cell sarcoma]]. | ||
*Epithelioid [[gastrointestinal stromal tumour]]. | *Epithelioid [[gastrointestinal stromal tumour]]. | ||
*[[Synovial sarcoma]], primitive round cell type. | |||
*Sarcomas in the ''[[small round cell tumours]]'' group, e.g. [[Ewing sarcoma]]. | |||
Note: | |||
*An exhaustive [[DDx]] is found in ''[[large epithelioid tumours]]'' and ''[[small round cell tumours]]''. | |||
==See also== | ==See also== | ||
*[[Spindle cell lesions]]. | *[[Spindle cell lesions]]. | ||
*[[Basics]]. | |||
*[[Pleomorphic tumours]]. | |||
*[[Large epithelioid tumours]]. | |||
==References== | ==References== | ||
Latest revision as of 06:55, 1 November 2014
Epithelioid cell lesions are very common in pathology. Malignant epithelioid lesions are most often carcinomas... but may be a large number different tumours.
Classification
Broadly, epithelioid lesions are split into:
General differential diagnosis
A short DDx:
- Carcinoma (primary and metastatic).
- Malignant melanoma.
- Sarcoma.
Epithelioid sarcomas
All rules are made to be broken... some epithelioid lesions are sarcomas:[1]
- Epithelioid sarcoma.
- Epithelioid angiosarcoma.
- Alveolar soft part sarcoma.
- Rhabdoid tumour.
Others:
- Clear cell sarcoma.
- Epithelioid gastrointestinal stromal tumour.
- Synovial sarcoma, primitive round cell type.
- Sarcomas in the small round cell tumours group, e.g. Ewing sarcoma.
Note:
- An exhaustive DDx is found in large epithelioid tumours and small round cell tumours.
See also
References
- ↑ Dei Tos AP, Wagner AJ, Modena P, Comandone A, Leyvraz S (August 2009). "Epithelioid soft tissue tumors". Semin. Oncol. 36 (4): 347–57. doi:10.1053/j.seminoncol.2009.06.005. PMID 19664495.