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Difference between revisions of "Invasive breast cancer"
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→Mucinous breast carcinoma: more
(→Mucinous breast carcinoma: more) |
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| Line 499: | Line 499: | ||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
* | *Malignant mucin producing glands. | ||
** | **Mucinous component should comprise >90% of the tumour.<ref name=pmid22006768>{{Cite journal | last1 = Dogan | first1 = E. | last2 = Aksoy | first2 = S. | last3 = Dizdar | first3 = O. | last4 = Arslan | first4 = C. | last5 = Dede | first5 = DS. | last6 = Ozisik | first6 = Y. | last7 = Altundag | first7 = K. | title = Pure mucinous carcinoma of the breast: a single center experience. | journal = J BUON | volume = 16 | issue = 3 | pages = 565-7 | month = | year = | doi = | PMID = 22006768 }}</ref> | ||
**Cells should float in the mucin - '''key feature'''. | |||
**Glands typically have irregular edges. | |||
**+/-Vessels within the mucin pools. | |||
DDx: | |||
*[[DCIS]] with a mucinous component. | |||
**Mucin has homogenous appearance, mucin lacks vascularization, mucin pools have a regular border. | |||
Note: | Note: | ||
*The amount of mucinous component to call ''[[mucinous carcinoma]]'' varies by anatomical site. | *The amount of mucinous component to call ''[[mucinous carcinoma]]'' varies by anatomical site. | ||
===IHC=== | |||
*ER +ve. | |||
*PR +ve. | |||
*HER2 -ve. | |||
==Adenoid cystic carcinoma of the breast== | ==Adenoid cystic carcinoma of the breast== | ||