Xanthogranulomatous cystitis
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Xanthogranulomatous cystitis is an uncommon chronic form of cystitis that may mimic malignancy.
General
- May mimic malignancy.[1][2]
Clinical features - generally nonspecific:[3]
- Dysuria (pain on urination).
- +/-Hematuria.
- Often history of renal stones or recurrent UTIs.
Gross
- Typically dome of urinary bladder (18 of 27 cases).[2]
Microscopic
Features:
- Foamy macrophages.
- Chronic inflammatory cells - typically lymphocytes and plasma cells.
- +/-Cholesterol clefts.
DDx:
IHC
Features:[1]
- CD68 +ve.
- Vimentin +ve.
See also
References
- ↑ 1.0 1.1 Wang, Y.; Han, XC.; Zheng, LQ.; Miao, WL. (2014). "Xanthogranulomatous cystitis imitating bladder neoplasm: a case report and review of literature.". Int J Clin Exp Pathol 7 (11): 8255-8. PMID 25550882.
- ↑ 2.0 2.1 Ali, AM.; Nelvigi, GG.; Keshavaiah, VG.; Ratkal, CS. (Oct 2014). "Extensive xanthogranulomatous cystitis mimicking bladder cancer.". Urol Ann 6 (4): 373-5. doi:10.4103/0974-7796.141018. PMID 25371622.
- ↑ Grivas, N. (Oct 2014). "Challenges in the diagnosis of xanthogranulomatous cystitis.". Urol Ann 6 (4): 375-6. doi:10.4103/0974-7796.141019. PMID 25371623.