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| Caption = CNS primitive neuroectodermal tumour [[H&E stain]]. | Prognosis = poor (WHO Grade IV)

'''Diffuse astrocytoma''' (AKA: ''diffuse, low-grade astrocytoma'') is a infiltrating astrocytoma occurring in the CNS white mat * Most common grade II WHO glioma in adults (peaks between 30-40 years).

...stem''' and the proposed '''Prostate cancer grading system endorsed by the WHO'''. ...eans: pattern 3 is present and dominant, pattern 4 is the remainder of the tumour - but present in a lesser amount than pattern 3.

| Prognosis = poor (WHO Grade IV) ''' Other CNS embryonal tumor''', was introduced in the WHO 2016 classification of CNS tumors. Some of these tumors of this category ha

{{hidden|Diagnosis|<center>[[Glioblastoma]], WHO grade IV</center> ...y IDH1/2 and ATRX alterations, while secondary GBM that develop from lower-grade precursor lesions usaually show nuclear [[ATRX]] loss and positive [[IDH-1]

...es''', abbreviated '''ETMR''', is a very rare [[neuropathology]] embryonal tumour with aggressive behaviour. * Histologically WHO grade IV tumor.

| Subtypes = [[malignant triton tumour]] ...nerve sheath tumour''', abbreviated '''MPNST''', is an uncommon malignant tumour of the nerve sheath.

*Benign tumour of the pineal gland. **WHO Grade I.

| Prognosis = subtype-dependent (WHO Grade IV) ...he [[cerebellum]] or dorsal brainstem. It is the most common malignant CNS tumour in children.

* [[Granular cell tumour]]. * [[Solitary fibrous tumour]] / Hemangiopericytoma.

*[[Germ cell tumour]]. ...|vauthors=Asa SL, Mete O, Perry A, Osamura RY |title=Overview of the 2022 WHO Classification of Pituitary Tumors |journal=Endocr Pathol |volume=33 |issue

...ht microscopy. This interveawing is called a syncytium. WHO Grading of the tumour is dependent of the [[Basics#Mitoses|mitotic]] activity (Picture 3) or hist ...als pseudosynzytialer Aspekt bezeichnet wird. Die Wertung des Tumors nach WHO ist abhängig von der mitotischen Aktivität (Bild 3), oder durch histologi

*Grade = inflammation/activity. A. [[File:1 etoh 3 680x512px.tif| Alcoholic hepatitis with Metavir stage IV fibrosis (advanced fibrosis/cirrhosis).]]