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Difference between revisions of "Lynch syndrome"
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*Non-endometrioid endometrial carcinoma.<ref name=pmid20396392>{{cite journal |author=Okuda T, Sekizawa A, Purwosunu Y, ''et al.'' |title=Genetics of endometrial cancers |journal=Obstet Gynecol Int |volume=2010 |issue= |pages=984013 |year=2010 |pmid=20396392 |pmc=2852605 |doi=10.1155/2010/984013 |url=}}</ref> | *Non-endometrioid endometrial carcinoma.<ref name=pmid20396392>{{cite journal |author=Okuda T, Sekizawa A, Purwosunu Y, ''et al.'' |title=Genetics of endometrial cancers |journal=Obstet Gynecol Int |volume=2010 |issue= |pages=984013 |year=2010 |pmid=20396392 |pmc=2852605 |doi=10.1155/2010/984013 |url=}}</ref> | ||
*Stomach carcinoma.<ref name=OMIM120435>{{OMIM|120435}}</ref> | *Stomach carcinoma.<ref name=OMIM120435>{{OMIM|120435}}</ref> | ||
**Significantly more common in males.<ref name=pmid19215248>{{Cite journal | last1 = Barrow | first1 = E. | last2 = Robinson | first2 = L. | last3 = Alduaij | first3 = W. | last4 = Shenton | first4 = A. | last5 = Clancy | first5 = T. | last6 = Lalloo | first6 = F. | last7 = Hill | first7 = J. | last8 = Evans | first8 = DG. | title = Cumulative lifetime incidence of extracolonic cancers in Lynch syndrome: a report of 121 families with proven mutations. | journal = Clin Genet | volume = 75 | issue = 2 | pages = 141-9 | month = Feb | year = 2009 | doi = 10.1111/j.1399-0004.2008.01125.x | PMID = 19215248 }}</ref> | |||
*Biliary tree carcinoma.<ref name=OMIM120435>{{OMIM|120435}}</ref> | *Biliary tree carcinoma.<ref name=OMIM120435>{{OMIM|120435}}</ref> | ||
*Pancreatic carcinoma.<ref name=OMIM120435>{{OMIM|120435}}</ref> | *Pancreatic carcinoma.<ref name=OMIM120435>{{OMIM|120435}}</ref> | ||
*Urinary system carcinoma.<ref name=OMIM120435>{{OMIM|120435}}</ref> | *Urinary system carcinoma.<ref name=OMIM120435>{{OMIM|120435}}</ref> | ||
**More common in the ureter than in sporadic cancers.<ref name=pmid21419447>{{Cite journal | last1 = Crockett | first1 = DG. | last2 = Wagner | first2 = DG. | last3 = Holmäng | first3 = S. | last4 = Johansson | first4 = SL. | last5 = Lynch | first5 = HT. | title = Upper urinary tract carcinoma in Lynch syndrome cases. | journal = J Urol | volume = 185 | issue = 5 | pages = 1627-30 | month = May | year = 2011 | doi = 10.1016/j.juro.2010.12.102 | PMID = 21419447 }}</ref> | |||
==Genes== | ==Genes== | ||