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Difference between revisions of "Esophagus"
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→Eosinophilic esophagitis: HPF -- definition
(update refs) |
(→Eosinophilic esophagitis: HPF -- definition) |
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==Eosinophilic esophagitis== | ==Eosinophilic esophagitis== | ||
===General=== | |||
Clinical: | Clinical: | ||
*Dyspepsia. | *Dyspepsia. | ||
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===Microscopy=== | ===Microscopy=== | ||
Features:<ref name=Ref_GLP19>{{Ref GLP|19}}</ref> | Features:<ref name=Ref_GLP19>{{Ref GLP|19}}</ref> | ||
*Mucosa with abundant eosinophils | *Mucosa with "abundant eosinophils". | ||
*Basal cell hyperplasia. | *Basal cell hyperplasia. | ||
*Papillae elongated. | *Papillae elongated. | ||
Notes: | |||
*Criteria for number of eosinophils/area is '''''highly variable'''''; there is a 23X fold variation in published values and only 11% actually define an area!<ref name=pmid17617209>{{cite journal |author=Dellon ES, Aderoju A, Woosley JT, Sandler RS, Shaheen NJ |title=Variability in diagnostic criteria for eosinophilic esophagitis: a systematic review |journal=Am. J. Gastroenterol. |volume=102 |issue=10 |pages=2300–13 |year=2007 |month=October |pmid=17617209 |doi=10.1111/j.1572-0241.2007.01396.x |url=}}</ref> | |||
*The ''Foundation Series'' book<ref name=Ref_GLP19>{{Ref GLP|19}}</ref> says: "> 20/HPF"); VL sees this definition as garbage, as "HPF" is not defined (see rant in the ''[[basics]]'' article). | |||
*Another paper says "> 15/HPF".<ref name=pmid19028328>{{cite journal |author=Liacouras CA |title=Eosinophilic esophagitis |journal=Gastroenterol. Clin. North Am. |volume=37 |issue=4 |pages=989–98, xi |year=2008 |month=December |pmid=19028328 |doi=10.1016/j.gtc.2008.09.004 |url=}}</ref> | |||
===Treatment=== | ===Treatment=== | ||