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Difference between revisions of "Renal transplant pathology"
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Renal transplant pathology (view source)
Revision as of 15:19, 7 November 2011
, 15:19, 7 November 2011→Transplant glomerulopathy: more +CAN
m (→Polyomavirus) |
(→Transplant glomerulopathy: more +CAN) |
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features:<ref name=Ref_DARP411>{{Ref DARP|411}}</ref> | ||
*Irregular GBM thickening - '''key feature'''. | |||
*Tram-tracking of basement membrane. | *Tram-tracking of basement membrane. | ||
*Increased mesangial matrix. | |||
*Segmental and global glomerular sclerosis. | |||
DDx (tram-tracking): | DDx (tram-tracking): | ||
*[[MPGN]]. | *[[MPGN]]. | ||
*[[Thrombotic microangiopathy]] (TMA). | *[[Thrombotic microangiopathy]] (TMA). | ||
==Chronic allograph nephropathy== | |||
===General=== | |||
*Month-years post-transplant. | |||
*Gradual decline in graft function. | |||
===Microscopic=== | |||
Features:<ref name=Ref_DARP411>{{Ref DARP|411}}</ref> | |||
*Arterial & arteriolar luminal narrowing - '''key feature'''. | |||
**Due to intimal and medial thickening. | |||
*Interstitial fibrosis and renal tubular atrophy. | |||
==Calcineurin-inhibitor toxicity== | ==Calcineurin-inhibitor toxicity== | ||