Talk:Renal transplant pathology

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Allograft biopsy categories (Banff 97):[1]

Type Key morphologic finding
Normal no inflammation
Suspicious for acute rejection focal mild tubulitis (1-4 mononuclear cells/tubular cross section)
Acute/active rejection tubulitis (>4 mononuclear cells/tubular cross section); see separate table for grading
Chronic/sclerosing allograft nephropathy interstitial fibrosis and tubular atrophy; see separate table for grading
Type Key morphologic finding

Acute/active rejection

Acute/active rejection in allograft biopsies (Banff 97):[1]

Grade Key morphologic finding
IA 4< mononuclear cell/tubular cross section or 10 tubular cells <10; >25% of parenchyma
IB >10 mononuclear cell/tubular cross section or 10 tubular cells; >25% of parenchyma
IIA mild-to-moderate intimal arteritis; <=25% of luminal area
IIB severe intimal arteritis; >25% of luminal area
III transmural arteritis and/or fibrinoid necrosis
  1. 1.0 1.1 Fogo, Agnes B.; Kashgarian, Michael (2005). Diagnostic Atlas of Renal Pathology: A Companion to Brenner and Rector's The Kidney 7E (1st ed.). Saunders. pp. 400. ISBN 978-1416028710.