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Difference between revisions of "Breast pathology"
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→Sclerosing adenosis
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Acini are smaller than usual and there are more of them | *Acini are smaller than usual and there are more of them. | ||
**Acini often slit-like. | |||
*Fibrosis (scleroses) - pink on H&E surrounds the acini. | *Fibrosis (scleroses) - pink on H&E surrounds the acini. | ||
**Can mimic a [[dysmoplastic reaction]]. | **Can mimic a [[dysmoplastic reaction]]. | ||
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Notes: | Notes: | ||
*The acini should: | *The acini should: | ||
**Be in lobular arrangements, i.e. in groups (benign appearance at low power). | **Be in lobular arrangements, i.e. in groups (benign appearance at low power) - '''key feature'''. | ||
**Have two cell layers like well-behaved breast glands do - | **Have two cell layers like well-behaved breast glands do. | ||
DDx: | |||
*Low-grade ductal carcinoma. | |||
=Lesions with increased risk of malignancy= | =Lesions with increased risk of malignancy= | ||