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Difference between revisions of "Prostate gland"
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==Atrophy== | ==Atrophy== | ||
===General=== | |||
*Small glands (may mimic Gleason score 3 pattern). | *Small glands (may mimic Gleason score 3 pattern). | ||
===Microscopic=== | |||
Features: | |||
*Glands often have a jagged edges/prows (in cancer the glands tend to have round edges). | *Glands often have a jagged edges/prows (in cancer the glands tend to have round edges). | ||
**Prow = forward most part of a ship's bow that cuts through the water.<ref>[http://en.wikipedia.org/wiki/Prow http://en.wikipedia.org/wiki/Prow]</ref> | **Prow = forward most part of a ship's bow that cuts through the water.<ref>[http://en.wikipedia.org/wiki/Prow http://en.wikipedia.org/wiki/Prow]</ref> | ||
***You may have come across ''prow'' in the context of [[breast cancer]], i.e. ''tubular carcinoma''. | ***You may have come across ''prow'' in the context of [[breast cancer]], i.e. ''tubular carcinoma''. | ||
*Atrophic glands are often hyperchromatic.<ref>SN. June 3, 2009.</ref> | *Atrophic glands are often hyperchromatic.<ref>SN. June 3, 2009.</ref> | ||
*Scant cytoplasm - usually. | |||
Negatives: | Negatives: | ||
*Nuclei like normal. | *Nuclei like normal, i.e. nucleoli uncommon. | ||
*Should have two cell layers, i.e. epithelial and myoepithelial (may be difficult to see). | *Should have two cell layers, i.e. epithelial and myoepithelial (may be difficult to see). | ||