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Difference between revisions of "Fibroblastic/myofibroblastic tumours"
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Fibroblastic/myofibroblastic tumours (view source)
Revision as of 04:25, 4 October 2011
, 04:25, 4 October 2011→Adult fibrosarcoma: mv infantile fibrosarc here
(→Calcifying fibrous tumour: +adult fibrosarcoma) |
(→Adult fibrosarcoma: mv infantile fibrosarc here) |
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*Vimentin. | *Vimentin. | ||
*SMA. | *SMA. | ||
==Congenital-infantile fibrosarcoma== | |||
:Should not be confused with ''[[adult fibrosarcoma]]''. | |||
===General=== | |||
*Locally aggressive. | |||
===Microscopic=== | |||
Features:<ref name=pmid7839472>{{Cite journal | last1 = Corsi | first1 = A. | last2 = Boldrini | first2 = R. | last3 = Bosman | first3 = C. | title = Congenital-infantile fibrosarcoma: study of two cases and review of the literature. | journal = Tumori | volume = 80 | issue = 5 | pages = 392-400 | month = Oct | year = 1994 | doi = | PMID = 7839472 }}</ref> | |||
*Spindle cell lesions. | |||
===Molecular=== | |||
Characteristic finding:<ref>{{Cite journal | last1 = Sheng | first1 = WQ. | last2 = Hisaoka | first2 = M. | last3 = Okamoto | first3 = S. | last4 = Tanaka | first4 = A. | last5 = Meis-Kindblom | first5 = JM. | last6 = Kindblom | first6 = LG. | last7 = Ishida | first7 = T. | last8 = Nojima | first8 = T. | last9 = Hashimoto | first9 = H. | title = Congenital-infantile fibrosarcoma. A clinicopathologic study of 10 cases and molecular detection of the ETV6-NTRK3 fusion transcripts using paraffin-embedded tissues. | journal = Am J Clin Pathol | volume = 115 | issue = 3 | pages = 348-55 | month = Mar | year = 2001 | doi = 10.1309/3H24-E7T7-V37G-AKKQ | PMID = 11242790 }}</ref> | |||
*t(12;15)(p13;q25) | |||
**Gene fusion ETV6-NTRK3. | |||
==See also== | ==See also== | ||