Difference between revisions of "Fibroblastic/myofibroblastic tumours"

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→‎Calcifying fibrous tumour: +adult fibrosarcoma
(→‎Calcifying fibrous tumour: +adult fibrosarcoma)
Line 266: Line 266:
*Psammomatous calcifications.
*Psammomatous calcifications.
*Focal plasma cells at the periphery.
*Focal plasma cells at the periphery.
==Adult fibrosarcoma==
*[[AKA]] ''fibrosarcoma''.
*Should '''not''' be confused with [[infantile fibrosarcoma]].
===General===
*Malignant.
*Older adults.
*Locations: head & neck, extremities.
===Microscopic===
Feature:<ref name=Ref_WMSP611>{{Ref WMSP|611}}</ref>
*Spindle cell lesion.
*Herring bone pattern - '''key feature'''.
*Mitoses.
DDx (herring bone):
*MPNST.
*Synovial sarcoma.
*Fibrosarcoma.
DDx:
*[[DFSP]] - t(17;22).
*Congenital-infantile fibrosarcoma - t(12;15) ETV6/NTRK3.
*[[Solitary fibrous tumour]].
*[[Synovial sarcoma]] - t(X;18) SYT/SSX.
*[[MPNST]].
Images:
*
===IHC===
Features:<ref name=Ref_WMSP611>{{Ref WMSP|611}}</ref>
*Vimentin.
*SMA.


==See also==
==See also==
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