Difference between revisions of "Breast pathology"

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908 bytes added ,  01:29, 4 October 2011
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#There is stuff about ''intracanalicular'' vs. ''pericanalicular''.<ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970216-9 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970216-9]. Accessed on: 16 March 2011.</ref>  It is irrelevant; there is no prognostic difference between the two.
#There is stuff about ''intracanalicular'' vs. ''pericanalicular''.<ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970216-9 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970216-9]. Accessed on: 16 March 2011.</ref>  It is irrelevant; there is no prognostic difference between the two.
#Do '''not''' comment on the margin - it is irrelevant.
#Do '''not''' comment on the margin - it is irrelevant.
====Juvenile variant====
Features (juvenile variant):
*"Looks more malignant":
**More mitoses.
**More atypical nuclei.
**More cellular.
Note:
*The ''juvenile variant'', as the name suggests, is typically found in younger patients.


====Phyllodes tumour vs. fibroadenoma====
====Phyllodes tumour vs. fibroadenoma====
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Tx:  
Tx:  
* Wide excision for phyllodes vs. local excision for fibroadenoma.
* Wide excision for phyllodes vs. local excision for fibroadenoma.
====Variants====
Four variants are described:<ref>{{Ref WMSP|262}}</ref>
#Juvenile.
#Complex.
#Myxoid.
#Cellular.
=====Juvenile variant=====
*As the name suggests, is typically found in younger patients.
*Classic history: rapid growth.
Features (juvenile variant):<ref>URL: [http://www.breastpathology.info/fibro_variants.html#juvenile http://www.breastpathology.info/fibro_variants.html#juvenile]. Accessed on: 3 October 2011.</ref>
*Stromal and epithelial hyperplasia - '''key feature'''.
*Mitoses uncommon.
=====Myxoid=====
*May be associated with ''[[Carney's complex]]''.
Features:
*Myxoid stroma.
=====Cellular=====
Features (cellular variant):
*Cellular.
*Mitoses.
=====Complex=====
*Contain proliferative epithelium which outside and inside a fibroadenoma is associated with an increased risk of malignancy.
Features:<ref>URL: [http://www.breastpathology.info/fibro_variants.html#complex http://www.breastpathology.info/fibro_variants.html#complex]. Accessed on: 3 October 2011.</ref>
# [[Apocrine metaplasia]].
# [[Sclerosing adenosis]].
# Cysts.<ref>MS. 3 October 2011.</ref>
# Calcification.<ref>MS. 3 October 2011.</ref>


==Phyllodes tumour==
==Phyllodes tumour==
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