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Pediatric pathology (view source)
Revision as of 22:07, 19 September 2011
, 22:07, 19 September 2011→Juvenile xanthogranuloma: more
(→Juvenile xanthogranuloma: more) |
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*Abbreviated as ''JXG''. | *Abbreviated as ''JXG''. | ||
*[[AKA]] nevoxanthoendothelioma. | *[[AKA]] nevoxanthoendothelioma. | ||
*In adults ''adult xanthogranuloma''.<ref name=Ref_Derm622>{{Ref Derm|622}}</ref> | |||
===General=== | ===General=== | ||
* | *Usually in children and infants, may be in adults.<ref name=Ref_Derm622>{{Ref Derm|622}}</ref> | ||
*Most common form of non–Langerhans cell histiocytosis.<ref name=emed_jxg>URL: [http://emedicine.medscape.com/article/1111629-diagnosis http://emedicine.medscape.com/article/1111629-diagnosis]. Accessed on: 3 February 2011.</ref> | *Most common form of non–Langerhans cell histiocytosis.<ref name=emed_jxg>URL: [http://emedicine.medscape.com/article/1111629-diagnosis http://emedicine.medscape.com/article/1111629-diagnosis]. Accessed on: 3 February 2011.</ref> | ||
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*+/-Touton [[giant cell]] - '''key feature'''. | *+/-Touton [[giant cell]] - '''key feature'''. | ||
**Large multi-nucleated cells where nuclei are distributed at the cell periphery. | **Large multi-nucleated cells where nuclei are distributed at the cell periphery. | ||
DDx: | |||
*[[Langerhans cell histiocytosis]]. | |||
Notes: | |||
*Must prove they are non-Langerhans cell histiocytes, esp. if no Touton giant cells. | |||
Images: | Images: | ||
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*[http://commons.wikimedia.org/w/index.php?title=File:Juvenile_xanthogranuloma_-_intermed_mag.jpg Juvenile xanthogranuloma - intermed. mag. (WC)]. | *[http://commons.wikimedia.org/w/index.php?title=File:Juvenile_xanthogranuloma_-_intermed_mag.jpg Juvenile xanthogranuloma - intermed. mag. (WC)]. | ||
*[http://commons.wikimedia.org/wiki/File:Juvenile_xanthogranuloma_-_very_high_mag.jpg Touton giant cells in a juvenile xanthogranuloma - very high mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Juvenile_xanthogranuloma_-_very_high_mag.jpg Touton giant cells in a juvenile xanthogranuloma - very high mag. (WC)]. | ||
===IHC=== | ===IHC=== | ||