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Difference between revisions of "Medical liver disease"
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===Epidemiology=== | ===Epidemiology=== | ||
*Female>male (~9:1).<ref>DCHH | *Female>male (~9:1).<ref>{{Ref DCHH|162}}</ref> | ||
*Usually middle age. | *Usually middle age. | ||
*Associated with other autoimmune conditions (Sjogren's syndrome, progressive systemic sclerosis, celiac). | *Associated with other autoimmune conditions (Sjogren's syndrome, progressive systemic sclerosis, celiac). | ||
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*[http://www.gidesigns.net/images/MC-copper-flower-garland-L.jpg Garland - wreath of flowers (gidesigns.net)]. | *[http://www.gidesigns.net/images/MC-copper-flower-garland-L.jpg Garland - wreath of flowers (gidesigns.net)]. | ||
DDx:<ref>DCHH | DDx:<ref>{{Ref DCHH|163}}</ref> | ||
*Sarcoidosis (if granulomas present). | *Sarcoidosis (if granulomas present). | ||
*PSC, viral hepatitis, AIH, drugs, Hodgkin's lymphoma<ref name=pmid19131796>Vanishing bile duct syndrome and Hodgkin disease: a case series and review of the literature. Pass AK, McLin VA, Rushton JR, Kearney DL, Hastings CA, Margolin JF. J Pediatr Hematol Oncol. 2008 Dec;30(12):976-80. PMID 19131796.</ref> | *PSC, viral hepatitis, AIH, drugs, Hodgkin's lymphoma<ref name=pmid19131796>Vanishing bile duct syndrome and Hodgkin disease: a case series and review of the literature. Pass AK, McLin VA, Rushton JR, Kearney DL, Hastings CA, Margolin JF. J Pediatr Hematol Oncol. 2008 Dec;30(12):976-80. PMID 19131796.</ref> | ||
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Microscopic: | Microscopic: | ||
*Non-specific findings. | *Non-specific findings. | ||
**+/-Eosinophils.<ref>DCHH | **+/-Eosinophils.<ref>{{Ref DCHH|166}}</ref> | ||
**+/-Steatosis - periportal macrovesicular, microvesicular. | **+/-Steatosis - periportal macrovesicular, microvesicular. | ||