Difference between revisions of "Dermal cysts"

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Dermal cysts (view source)

Revision as of 15:36, 9 September 2011

1,319 bytes removed ,  15:36, 9 September 2011
split-out EM, SJS, TEN
(split-out EM, SJS, TEN)
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==Epidermal necrosis==
==Epidermal necrosis==
===General===
*This may be cystic. It is covered in the ''[[epidermal necrosis]]'' article, which covers [[erythema multiforme]], [[Steven-Johnson syndrome]] and [[toxic epidermal necrolysis]].
Full thickness DDx:
*Erythema multiform (EM).
*Toxic epidermal necrolysis (TEN).
*Stevens-Johnson syndrome (SJS).
*Trauma.
*Others. (???)
 
Partial thickness DDx:
*Staphylococcal scalded skin syndrome.
*Trauma. (???)
*Others. (???)
 
Notes:
*SJS and TEN are on a spectrum, EM (depending on who you ask) is considered separate.
 
===Erythema multiforme===
*Abbreviated ''EM''.
====General====
Features:<ref name=Ref_PBoD8_1189>{{Ref PBoD8|1189}}</ref>
*Hypersensitivity disorder due to a drug ''or'' infection.
**Associated with the following: [[HSV]], Mycoplasma, [[Histoplasma]], others.
 
Clinical:
*Target-like lesion.
 
====Microscopic====
Features:<ref name=Ref_PBoD8_1189>{{Ref PBoD8|1189}}</ref>
*Lymphocytic interface dermatitis (lymphocytes at the dermal-epidermal junction).
*Necrotic/degenerative keratinocytes - '''key feature'''.
*+/-Epidermal blistering.
*+/-Epidermal sloughing.
 
===Stevens-Johnson Syndrome===
*Abbreviated SJS.
====General====
Rx causes of SJS:
*NSAIDs.
*Anticonvulsants.
*Sulfonamides.
*Penicillins.
 
====Microscopic====
Features:
*Similar [[erythema multiforme]].
 
===Toxic epidermal necrolysis===
*Abbreviated TEN.
====General====
*TEN more severe form SJS.
 
Definition:
*>30% sheet-like epidermal detachment, diffuse erythema, severe mucous membrane involvement.
*Most TEN (80%) Rx-related, only 50% of SJS Rx-related.
 
====Microscopic====
Features:
*Like [[erythema multiforme]] - but usu. less inflammation.<ref>S. Sade. 8 September 2011.</ref>


==Venous lake==
==Venous lake==
Michael
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