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m (→Cysts) |
(→EM, SJS, TEN: more) |
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Line 9: | Line 9: | ||
*Milicem. | *Milicem. | ||
==EM | ==Epidermal necrosis== | ||
*SJS and TEN are on a spectrum, EM is considered separate. | ===General=== | ||
Full thickness DDx: | |||
*Erythema multiform (EM). | |||
*Toxic epidermal necrolysis (TEN). | |||
*Stevens-Johnson syndrome (SJS). | |||
*Trauma. | |||
*Others. (???) | |||
Partial thickness DDx: | |||
*Staphylococcal scalded skin syndrome. | |||
*Trauma. (???) | |||
*Others. (???) | |||
Notes: | |||
*SJS and TEN are on a spectrum, EM (depending on who you ask) is considered separate. | |||
===Erythema multiforme=== | ===Erythema multiforme=== | ||
Line 16: | Line 30: | ||
====General==== | ====General==== | ||
Features:<ref name=Ref_PBoD8_1189>{{Ref PBoD8|1189}}</ref> | Features:<ref name=Ref_PBoD8_1189>{{Ref PBoD8|1189}}</ref> | ||
*Hypersensitivity disorder to a drug or | *Hypersensitivity disorder due to a drug ''or'' infection. | ||
**Associated with the following: [[HSV]], Mycoplasma, Histoplasma, others. | **Associated with the following: [[HSV]], Mycoplasma, [[Histoplasma]], others. | ||
Clinical: | Clinical: | ||
Line 31: | Line 45: | ||
===Stevens-Johnson Syndrome=== | ===Stevens-Johnson Syndrome=== | ||
*Abbreviated SJS. | *Abbreviated SJS. | ||
====General==== | |||
Rx causes of SJS: | Rx causes of SJS: | ||
*NSAIDs. | *NSAIDs. | ||
Line 38: | Line 52: | ||
*Penicillins. | *Penicillins. | ||
===Toxic | ====Microscopic==== | ||
Features: | |||
*Similar [[erythema multiforme]]. | |||
===Toxic epidermal necrolysis=== | |||
*Abbreviated TEN. | *Abbreviated TEN. | ||
====General==== | |||
TEN more severe form SJS. | *TEN more severe form SJS. | ||
Definition: | Definition: | ||
*>30% sheet-like epidermal detachment, diffuse erythema, severe mucous membrane involvement. | *>30% sheet-like epidermal detachment, diffuse erythema, severe mucous membrane involvement. | ||
*Most TEN (80%) Rx-related, only 50% of SJS Rx-related. | *Most TEN (80%) Rx-related, only 50% of SJS Rx-related. | ||
====Microscopic==== | |||
Features: | |||
*Like [[erythema multiforme]] - but usu. less inflammation.<ref>S. Sade. 8 September 2011.</ref> | |||
==Venous lake== | ==Venous lake== |
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