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Difference between revisions of "Neurodegenerative diseases"
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Neurodegenerative diseases (view source)
Revision as of 03:56, 30 August 2011
, 03:56, 30 August 2011→Parkinson disease
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*Abnormally pale substantia nigra. | *Abnormally pale substantia nigra. | ||
**Pigmentation increases with age. | **Pigmentation increases with age. | ||
* | *Pale ''[[locus ceruleus]]''. | ||
Notes: | Notes: | ||
| Line 295: | Line 295: | ||
===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=Ref_PBoD8_1319>{{Ref PBoD8|1319}}</ref> | Features:<ref name=Ref_PBoD8_1319>{{Ref PBoD8|1319}}</ref> | ||
*Loss of pigmented (catecholaminergic) neurons in the substantia nigra. | *Loss of pigmented (catecholaminergic) neurons in the substantia nigra and locus ceruleus. | ||
*Gliosis - due to neuron loss. | *Gliosis - due to neuron loss. | ||
*Lewy bodies (in remaining neurons) - '''key feature'''. | *Lewy bodies (in remaining neurons) - '''key feature'''. | ||