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Difference between revisions of "Gestational trophoblastic disease"
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Gestational trophoblastic disease (view source)
Revision as of 16:03, 15 August 2011
, 16:03, 15 August 2011→Entities - intermediate trophoblast: +table
(→Entities - intermediate trophoblast: +table) |
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=Entities - intermediate trophoblast= | =Entities - intermediate trophoblast= | ||
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto" | |||
! Entity | |||
! Key feature | |||
! Other histologic features | |||
! IHC | |||
! DDx | |||
! Other | |||
! Image | |||
|- | |||
| [[Placental site nodule]] | |||
| Key feature? | |||
| Other histologic features? | |||
| IHC? | |||
| DDx? | |||
| Other? | |||
| Image? | |||
|- | |||
| [[Exaggerated placental site]] | |||
| Key feature? | |||
| Other histologic features? | |||
| MIB1 ~0% | |||
| [[PSTT]] | |||
| Other? | |||
| Image? | |||
|- | |||
| Placental site trophoblastic tumour | |||
| abundant cytoplasm - not clear | |||
| +/-multinucleation | |||
| MIB1 high | |||
| [[EPS]] | |||
| Other? | |||
| Image? | |||
|- | |||
| [[Epithelioid trophoblastic tumour]] | |||
| nests of cells in hyaline stroma | |||
| eosinophilic cytoplasm, central nucleus | |||
| p16-, MIB1 low | |||
| [[squamous carcinoma]] | |||
| Other? | |||
| Image? | |||
|- | |||
| [[Choriocarcinoma]] | |||
| polygonal cells with clear cytoplasm (cytotrophoblasts) | |||
| multinucleated cells with smudged nuclei (syncytiotrophoblasts), no [[chorionic villi]] | |||
| beta-hCG | |||
| DDx? | |||
| elevated beta-hCG (serum) | |||
| Image? | |||
|- <!-- | |||
| Entity? | |||
| Key feature? | |||
| Other histologic features? | |||
| IHC? | |||
| DDx? | |||
| Other? | |||
| Image? --> | |||
|} | |||
==Placental site nodule== | ==Placental site nodule== | ||
===General=== | ===General=== | ||