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Difference between revisions of "Gestational trophoblastic disease"
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Gestational trophoblastic disease (view source)
Revision as of 15:50, 15 August 2011
, 15:50, 15 August 2011→Entities - intermediate trophoblast
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=Entities - intermediate trophoblast= | =Entities - intermediate trophoblast= | ||
==Placental site nodule== | |||
===General=== | |||
*Benign. | |||
*Intermediate trophoblast remnants from a previous gestation.<ref name=pmid19332926>{{Cite journal | last1 = Jacob | first1 = S. | last2 = Mohapatra | first2 = D. | title = Placental site nodule: a tumor-like trophoblastic lesion. | journal = Indian J Pathol Microbiol | volume = 52 | issue = 2 | pages = 240-1 | month = | year = | doi = | PMID = 19332926 | url = http://www.ijpmonline.org/text.asp?2009/52/2/240/48931 }}</ref> | |||
===Microscopic=== | |||
Features:<ref name=pmid19332926/> | |||
*Paucicellular with hyaline material scattered cells. | |||
*Variable cell population: | |||
**Small-large cells. | |||
**Clear to eosinophilic cytoplasm. | |||
**+/-Multinucleation. | |||
Notes: | |||
*No mitotic activity. | |||
Images: | |||
*[http://www.gfmer.ch/selected_images_v2/detail_list.php?cat1=12&cat3=1256&stype=d PSN (gfmer.ch)] from ''Jacob and Mohapatra''.<ref name=pmid19332926/> | |||
DDx: | |||
*Invasive [[squamous cell carcinoma]]. | |||
**Can be sorted-out with IHC (SCC will typically be: p16 +ve, MIB1 +ve). | |||
==Exaggerated placental site== | ==Exaggerated placental site== | ||
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*[http://www.webpathology.com/image.asp?case=589&n=2 ETT (webpathology.com)].<ref name=webp_ett/> | *[http://www.webpathology.com/image.asp?case=589&n=2 ETT (webpathology.com)].<ref name=webp_ett/> | ||
*[http://www.gfmer.ch/selected_images_v2/detail_list.php?cat1=12&cat3=861&stype=d ETT - several images (gfmer.ch)]. | *[http://www.gfmer.ch/selected_images_v2/detail_list.php?cat1=12&cat3=861&stype=d ETT - several images (gfmer.ch)]. | ||
=See also= | =See also= | ||