Difference between revisions of "Langerhans cell histiocytosis"

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'''Langerhans cell histiocytosis''', abbreviated '''LCH''', is a rare genetic disorder of tissue macrophages. It broadly fits into the category of ''[[histiocytoses]]''.
'''Langerhans cell histiocytosis''', abbreviated '''LCH''', is a rare genetic disorder of tissue macrophages. It broadly fits into the category of ''[[histiocytoses]]''.


===General===
==General==
*Looks like eosinophilic granuloma of the lung - see ''[[Medical_lung_diseases#Pulmonary_Langerhans_cell_histiocytosis|medical lung diseases]]''.
*Looks like eosinophilic granuloma of the lung - see ''[[Medical_lung_diseases#Pulmonary_Langerhans_cell_histiocytosis|medical lung diseases]]''.


===Microscopic===
==Microscopic==
Features:
Features:
*Langerhans cells histiocytes - '''key feature'''.
*Langerhans cells histiocytes - '''key feature'''.
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*See ''[[lymph node pathology]]''.
*See ''[[lymph node pathology]]''.


===IHC===
==IHC==
*CD1a +ve.
*CD1a +ve.
*S100 +ve.
*S100 +ve.


===Electron microscopy===
==Electron microscopy==
*[[Birbeck granules]].
*[[Birbeck granules]].


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