Difference between revisions of "Breast pathology"

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1,246 bytes added ,  02:39, 31 May 2010
(reword intro)
(→‎Radial scar: more refs)
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==Radial scar==
==Radial scar==
*AKA ''complex sclerosing lesion''.
===General===
*May appear malignant on imaging.
*AKA '''''complex sclerosing lesion'''''.
*May appear malignant on imaging.<ref name=pmid11167596>{{cite journal |author=Ung OA, Lee WB, Greenberg ML, Bilous M |title=Complex sclerosing lesion: the lesion is complex, the management is straightforward |journal=ANZ J Surg |volume=71 |issue=1 |pages=35–40 |year=2001 |month=January |pmid=11167596 |doi= |url=}}</ref>
*Associated with subsequent elevated risk of breast cancer.<ref>URL: [http://www.cancer.org/docroot/NWS/content/NWS_1_1x_Radial_Scars.asp http://www.cancer.org/docroot/NWS/content/NWS_1_1x_Radial_Scars.asp]. Accessed on: 4 May 2010.</ref>
*Associated with subsequent elevated risk of breast cancer.<ref>URL: [http://www.cancer.org/docroot/NWS/content/NWS_1_1x_Radial_Scars.asp http://www.cancer.org/docroot/NWS/content/NWS_1_1x_Radial_Scars.asp]. Accessed on: 4 May 2010.</ref>
*Management - usu. surgical excision.<ref name=pmid14514771>{{cite journal |author=Kennedy M, Masterson AV, Kerin M, Flanagan F |title=Pathology and clinical relevance of radial scars: a review |journal=J. Clin. Pathol. |volume=56 |issue=10 |pages=721–4 |year=2003 |month=October |pmid=14514771 |pmc=1770086 |doi= |url=}}</ref>
===Gross===
*Spiculated mass.
Image: [http://commons.wikimedia.org/wiki/File:Radial_scar.jpg Radial scar - gross (WC)].


===Microscopic===
===Microscopic===
Feature:
Features:<ref name=pmid14514771>{{cite journal |author=Kennedy M, Masterson AV, Kerin M, Flanagan F |title=Pathology and clinical relevance of radial scars: a review |journal=J. Clin. Pathol. |volume=56 |issue=10 |pages=721–4 |year=2003 |month=October |pmid=14514771 |pmc=1770086 |doi= |url=}}</ref>
*Hyaline is the key.
*Sclerotic appearing (i.e. scar like) stroma with entrapped normal breast ducts and lobules.
**May mimic a desmoplastic reaction of stroma -- leading to a misdiagnosis of malignancy.


Notes:
*Histomorphologic appearance may mimic a desmoplastic reaction of stroma - leading to a misdiagnosis of malignancy.
*"Hyaline <nowiki>[pink stuff on H&E]</nowiki> is the key."<ref>RS. May 2010.</ref>


==Fibroadenoma==
==Fibroadenoma==
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