Difference between revisions of "Clear cell papillary renal cell tumour"

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Left Kidney Mass, Core Biopsy:
A. Left Kidney Mass, Radical Nephrectomy:
    - CLEAR CELL PAPILARY RENAL CELL TUMOUR, preliminary ISUP nucleolar grade 1 of 4, see comment.
- CLEAR CELL PAPILARY RENAL CELL TUMOUR, nucleolar grade 1 of 4, see comment.
    -- Margins clear.
    -- Please see synoptic report.


Comment:
Comment:
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The tumour stains as follows:  
The tumour stains as follows:  
POSITIVE: PAX8 (diffuse), CK7 (strong, diffuse), CK34betaE12 (strong, diffuse), vimentin (diffuse, strong), EMA (moderate, diffuse).
POSITIVE: PAX8 (strong, diffuse), CK7 (strong, diffuse), MA903 (strong, diffuse), CAIX (moderate, patchy cup-like), AE1/AE3 (moderate, diffuse), GATA3 (moderate, diffuse).
NEGATIVE: CD10.
NEGATIVE: CD10, AMACR.
 
The findings are in keeping with clear cell tubulopapillary renal cell tumour. These tumours were previously called "clear cell papillary renal cell carcinoma".


The findings are in keeping with clear cell papillary renal cell tumour. These tumours were previously called "clear cell papillary renal cell carcinoma".


These tumours have a highly favourable clinical behaviour.[1,2]  
These tumours have a highly favourable clinical behaviour.[1,2]  
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2. Pathology. 2020 Nov 19;S0031-3025(20)30957-0. DOI: 10.1016/j.pathol.2020.10.002
2. Pathology. 2020 Nov 19;S0031-3025(20)30957-0. DOI: 10.1016/j.pathol.2020.10.002
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===Biopsy===
Overlaps are described between clear cell RCC and clear cell papillary renal cell tumour.<ref name=pmid26752401>{{cite journal |vauthors=Dhakal HP, McKenney JK, Khor LY, Reynolds JP, Magi-Galluzzi C, Przybycin CG |title=Renal Neoplasms With Overlapping Features of Clear Cell Renal Cell Carcinoma and Clear Cell Papillary Renal Cell Carcinoma: A Clinicopathologic Study of 37 Cases From a Single Institution |journal=Am J Surg Pathol |volume=40 |issue=2 |pages=141–54 |date=February 2016 |pmid=26752401 |doi=10.1097/PAS.0000000000000583 |url=}}</ref> ''Clear cell papillary renal cell tumour'' may also be seen in conjunction with other types of RCC.<ref name=pmid26857533>{{cite journal |authors=Shao T, Yousef P, Shipilova I, Saleeb R, Lee JY, Krizova A |title=Clear cell papillary renal cell carcinoma as part of histologically discordant multifocal renal cell carcinoma: A case report and review of literature |journal=Pathol Res Pract |volume=212 |issue=3 |pages=229–33 |date=March 2016 |pmid=26857533 |doi=10.1016/j.prp.2015.12.007 |url=}}</ref>


==See also==
==See also==
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