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==Sign out== | ==Sign out== | ||
<pre> | <pre> | ||
Left Kidney Mass, | A. Left Kidney Mass, Radical Nephrectomy: | ||
- CLEAR CELL PAPILARY RENAL CELL TUMOUR, nucleolar grade 1 of 4, see comment. | |||
-- Margins clear. | |||
-- Please see synoptic report. | |||
Comment: | Comment: | ||
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The tumour stains as follows: | The tumour stains as follows: | ||
POSITIVE: PAX8 (diffuse), CK7 (strong, diffuse), | POSITIVE: PAX8 (strong, diffuse), CK7 (strong, diffuse), MA903 (strong, diffuse), CAIX (moderate, patchy cup-like), AE1/AE3 (moderate, diffuse), GATA3 (moderate, diffuse). | ||
NEGATIVE: CD10 | NEGATIVE: CD10, AMACR. | ||
The findings are in keeping with clear cell papillary renal cell tumour. These tumours were previously called "clear cell papillary renal cell carcinoma". | |||
These tumours have a highly favourable clinical behaviour.[1,2] | These tumours have a highly favourable clinical behaviour.[1,2] | ||
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2. Pathology. 2020 Nov 19;S0031-3025(20)30957-0. DOI: 10.1016/j.pathol.2020.10.002 | 2. Pathology. 2020 Nov 19;S0031-3025(20)30957-0. DOI: 10.1016/j.pathol.2020.10.002 | ||
</pre> | </pre> | ||
===Biopsy=== | |||
Overlaps are described between clear cell RCC and clear cell papillary renal cell tumour.<ref name=pmid26752401>{{cite journal |vauthors=Dhakal HP, McKenney JK, Khor LY, Reynolds JP, Magi-Galluzzi C, Przybycin CG |title=Renal Neoplasms With Overlapping Features of Clear Cell Renal Cell Carcinoma and Clear Cell Papillary Renal Cell Carcinoma: A Clinicopathologic Study of 37 Cases From a Single Institution |journal=Am J Surg Pathol |volume=40 |issue=2 |pages=141–54 |date=February 2016 |pmid=26752401 |doi=10.1097/PAS.0000000000000583 |url=}}</ref> ''Clear cell papillary renal cell tumour'' may also be seen in conjunction with other types of RCC.<ref name=pmid26857533>{{cite journal |authors=Shao T, Yousef P, Shipilova I, Saleeb R, Lee JY, Krizova A |title=Clear cell papillary renal cell carcinoma as part of histologically discordant multifocal renal cell carcinoma: A case report and review of literature |journal=Pathol Res Pract |volume=212 |issue=3 |pages=229–33 |date=March 2016 |pmid=26857533 |doi=10.1016/j.prp.2015.12.007 |url=}}</ref> | |||
==See also== | ==See also== | ||
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