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Difference between revisions of "Small cell carcinoma of the lung"
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Small cell carcinoma of the lung (view source)
Revision as of 22:29, 16 January 2025
, 22:29, 16 January 2025no edit summary
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| Synonyms = | | Synonyms = | ||
| Micro = stippled chromatin, high [[NC ratio]] with scant basophilic cytoplasm, typically small cells (~2x [[RBC]] diameter), +/-nuclear moulding, nuclei with smudgy appearance ([[Azzopardi phenomenon]]), necrosis, [[mitoses]] | | Micro = stippled chromatin, high [[NC ratio]] with scant basophilic cytoplasm, typically small cells (~2x [[RBC]] diameter), +/-nuclear moulding, nuclei with smudgy appearance ([[Azzopardi phenomenon]]), necrosis, [[mitoses]] | ||
| Subtypes = large cell neuroendocrine carcinoma (LCNEC) | | Subtypes = histology: large cell neuroendocrine carcinoma (LCNEC); molecular subtypes: ASCL1, NEUROD1, POU2F3, YAP1 | ||
| LMDDx = poorly differentiated [[adenocarcinoma of the lung]], [[atypical carcinoid]], [[lung carcinoid]], metastatic [[small cell carcinoma]], [[lymphoma]], other [[small round blue cell tumours]] | | LMDDx = poorly differentiated [[adenocarcinoma of the lung]], [[atypical carcinoid]], [[lung carcinoid]], metastatic [[small cell carcinoma]], [[lymphoma]], other [[small round blue cell tumours]] | ||
| Stains = | | Stains = | ||