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Difference between revisions of "Papillary renal neoplasm with reverse polarity"
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Papillary renal neoplasm with reverse polarity (view source)
Revision as of 14:09, 16 August 2024
, 16 Augustno edit summary
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==IHC== | ==IHC== | ||
Features:<ref name=pmid31135486/> | Features:<ref name=pmid31135486/> | ||
*GATA3 +ve (43 of 43 cases<ref name=pmid37797754/>) - '''key stain'''. | |||
**Negative in other papillary RCCs.<ref name=pmid37797754/> | |||
*CK7 +ve (88% +ve, 37 of 42 cases<ref name=pmid37797754/>). | *CK7 +ve (88% +ve, 37 of 42 cases<ref name=pmid37797754/>). | ||
*CD10 +ve/-ve (50% +ve, 21 of 42 cases<ref name=pmid37797754/>). | *CD10 +ve/-ve (50% +ve, 21 of 42 cases<ref name=pmid37797754/>). | ||
*Vimentin -ve (all cases). | *Vimentin -ve (all cases). | ||
*CD117 -ve. | *CD117 -ve. | ||
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*EMA +ve. | *EMA +ve. | ||
*L1CAM +ve. | *L1CAM +ve. | ||
*PAX8 +ve. | |||
*AMACR -ve (4 of 43 cases<ref name=pmid37797754/>). | *AMACR -ve (4 of 43 cases<ref name=pmid37797754/>). | ||
*RCC -ve (1 of 43 cases<ref name=pmid37797754/>). | *RCC -ve (1 of 43 cases<ref name=pmid37797754/>). | ||
=== | ===Differentiating between papillary RCC and PRNRP=== | ||
Adapted from Kim ''et al.'':<ref name=pmid37797754/> | |||
{| class="wikitable sortable" | {| class="wikitable sortable" | ||
!Diagnosis | !Diagnosis | ||