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Difference between revisions of "Sertoli cell tumour"
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| LMDDx = [[granulosa cell tumour]], epithelioid [[adenomatoid tumour]], [[sertoli cell nodule]], [[Sertoli-Leydig tumour]] | | LMDDx = [[granulosa cell tumour]], epithelioid [[adenomatoid tumour]], [[sertoli cell nodule]], [[Sertoli-Leydig tumour]] | ||
| Stains = | | Stains = | ||
| IHC = SF-1 +ve, alpha-inhibin +ve, calretinin +ve/-ve, | | IHC = [[SF-1]] +ve, alpha-inhibin +ve, calretinin +ve/-ve, | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
| Line 72: | Line 72: | ||
**Negative beta-catenin should make one consider other diagnoses.{{fact}} | **Negative beta-catenin should make one consider other diagnoses.{{fact}} | ||
**May be negative in malignant sertoli cell tumours. | **May be negative in malignant sertoli cell tumours. | ||
*SF-1 +ve.<ref name=pmid23165333>{{cite journal |authors=Sangoi AR, McKenney JK, Brooks JD, Higgins JP |title=Evaluation of SF-1 expression in testicular germ cell tumors: a tissue microarray study of 127 cases |journal=Appl Immunohistochem Mol Morphol |volume=21 |issue=4 |pages=318–21 |date=July 2013 |pmid=23165333 |doi=10.1097/PAI.0b013e318277cf5a |url=}}</ref> | *[[SF-1]] +ve.<ref name=pmid23165333>{{cite journal |authors=Sangoi AR, McKenney JK, Brooks JD, Higgins JP |title=Evaluation of SF-1 expression in testicular germ cell tumors: a tissue microarray study of 127 cases |journal=Appl Immunohistochem Mol Morphol |volume=21 |issue=4 |pages=318–21 |date=July 2013 |pmid=23165333 |doi=10.1097/PAI.0b013e318277cf5a |url=}}</ref> | ||
**Germ cell tumours -ve. | **Germ cell tumours -ve. | ||