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Difference between revisions of "SMARCA4-deficient sinonasal carcinoma"
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SMARCA4-deficient sinonasal carcinoma (view source)
Revision as of 16:13, 20 December 2023
, 16:13, 20 December 2023no edit summary
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'''SMARCA4-deficient sinonasal carcinoma''' is an emerging type of sinonasal carcinoma.<ref name=pmid31934917>{{cite journal |vauthors=Agaimy A, Jain D, Uddin N, Rooper LM, Bishop JA |title=SMARCA4-deficient Sinonasal Carcinoma: A Series of 10 Cases Expanding the Genetic Spectrum of SWI/SNF-driven Sinonasal Malignancies |journal=Am J Surg Pathol |volume=44 |issue=5 |pages=703–710 |date=May 2020 |pmid=31934917 |doi=10.1097/PAS.0000000000001428 |url=}}</ref> | '''SMARCA4-deficient sinonasal carcinoma''' is an emerging type of sinonasal carcinoma.<ref name=pmid31934917>{{cite journal |vauthors=Agaimy A, Jain D, Uddin N, Rooper LM, Bishop JA |title=SMARCA4-deficient Sinonasal Carcinoma: A Series of 10 Cases Expanding the Genetic Spectrum of SWI/SNF-driven Sinonasal Malignancies |journal=Am J Surg Pathol |volume=44 |issue=5 |pages=703–710 |date=May 2020 |pmid=31934917 |doi=10.1097/PAS.0000000000001428 |url=}}</ref> | ||
==General== | |||
*Evolving entity - previously diagnosed as [[SNUC]], [[neuroendocrine carcinoma]].<ref name=pmid34871352>{{cite journal |authors=Kakkar A, Ashraf SF, Rathor A, Adhya AK, Mani S, Sikka K, Jain D |title=SMARCA4/BRG1-Deficient Sinonasal Carcinoma |journal=Arch Pathol Lab Med |volume=146 |issue=9 |pages=1122–1130 |date=September 2022 |pmid=34871352 |doi=10.5858/arpa.2021-0001-OA |url=}}</ref> | |||
==Microscopic== | ==Microscopic== | ||
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*Poorly differentiated tumour with large or small cells. | *Poorly differentiated tumour with large or small cells. | ||
DDx:<ref>{{cite journal |authors=Kakkar A, Ashraf SF, Rathor A, Adhya AK, Mani S, Sikka K, Jain D |title=SMARCA4/BRG1-Deficient Sinonasal Carcinoma |journal=Arch Pathol Lab Med |volume=146 |issue=9 |pages=1122–1130 |date=September 2022 |pmid=34871352 |doi=10.5858/arpa.2021-0001-OA |url=}}</ref> | DDx:<ref name=pmid34871352>{{cite journal |authors=Kakkar A, Ashraf SF, Rathor A, Adhya AK, Mani S, Sikka K, Jain D |title=SMARCA4/BRG1-Deficient Sinonasal Carcinoma |journal=Arch Pathol Lab Med |volume=146 |issue=9 |pages=1122–1130 |date=September 2022 |pmid=34871352 |doi=10.5858/arpa.2021-0001-OA |url=}}</ref> | ||
*[[Sinonasal undifferentiated carcinoma]] (SNUC). | *[[Sinonasal undifferentiated carcinoma]] (SNUC). | ||
*Neuroendocrine carcinoma - [[small cell carcinoma]] and [[large cell neuroendocrine carcinoma]]. | *Neuroendocrine carcinoma - [[small cell carcinoma]] and [[large cell neuroendocrine carcinoma]]. | ||