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Difference between revisions of "Astrocytoma"
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→Uncommon Astrocytomas: HGAP
Jensflorian (talk | contribs) (diffuse vs. adult category) |
Jensflorian (talk | contribs) (→Uncommon Astrocytomas: HGAP) |
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{{Main|Diffuse hemispheric glioma, H3 G34-mutant}} | {{Main|Diffuse hemispheric glioma, H3 G34-mutant}} | ||
==High-grade astrocytoma with piloid features== | |||
* Frequent in posterior fossa (75%). | |||
* 1-3% of all brain tumors. | |||
* Histology may resemble Glionblastoma or Pleomorphic xanthoastrocytoma. | |||
* Tumor is enriched for piloid cell processes. | |||
* ATRX nuclear loss is frequent. | |||
* Usu. MAPK-pathway alterations + CDKN2A homozygous deletion. | |||
* Distinct methylation profile. | |||
* Depreceated terminology: Anaplastic pilocytic astrocytoma. | |||
==Gliomatosis cerebri== | ==Gliomatosis cerebri== | ||