Difference between revisions of "Pituitary gland"

Pituitary gland (view source)

186 bytes added , 10:24, 30 September 2022

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 ! Transcription factor
 |-
-|
-| Somatotroph adenoma
-| Densely and sparsely granulated adenoma, Mammosomatotroph adenoma, Mixed GH and PRL adenoma
-| GH +/- PRL
 | PIT1
+| Somatotroph tumor
+| Densely and sparsely granulated tumor
+| GH, a-subunit+/-, CK+
+| PIT1
+|-
+| PIT1
+| Lactotroph tumor
+| Densely and sparsely granulated tumor
+| PRL, CK-ve or weak
+| PIT1, [[Estrogen receptor|ER]]
 |-
-|
+| PIT1
-| Lactotroph adenoma
+| Mammosomatotroph tumor
-| Densely and sparsely granulated adenoma, Acidophilic stem cell adenoma
+|
-| PRL
+| GH, PRL (usu. less), CK perinuclear +ve
 | PIT1, [[Estrogen receptor|ER]]
 |-
+| PIT1
+| Thyrotroph tumor
 |
-| Thyrotroph adenoma
+| TSH, CK-ve or weak
-|
+| PIT1, GATA3
-| TSH
+|-
-| PIT1, [[Estrogen receptor|ER]]
+| PIT1
+| Mature plurihormonal PIT1 lineage tumor
+|
+| GH, PRL, TSH, a-subunit +/-ve
+| PIT1, [[Estrogen receptor|ER]], GATA3
 |-
 |