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Difference between revisions of "Human papillomavirus"
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(Removed redirect to Viruses#Human papillomavirus) Tag: Removed redirect |
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[[Image:High grade squamous intraepithelial lesion - 2 - p16 -- high mag.jpg|thumb|Micrograph showing block positive [[p16]] immunostaining in [[high-grade squamous intraepithelial lesion]] of the cervix. ''p16'' is commonly used as a surrogate marker for human papillomavirus (HPV). (WC)]] | |||
'''Human papillomavirus''', abbreviated '''HPV''', is virus implicated in a large number of [[cancer]]s. | '''Human papillomavirus''', abbreviated '''HPV''', is virus implicated in a large number of [[cancer]]s. | ||
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*** Central location - nucleus should be smack in the middle of the cell. | *** Central location - nucleus should be smack in the middle of the cell. | ||
Images | ===Images=== | ||
<gallery> | |||
Image:Low-grade_squamous_intraepithelial_lesion.jpg | LSIL (WC). | |||
Image:Low-grade_sil_and_endocx.jpg | LSIL & endocervix (WC). | |||
</gallery> | |||
==IHC== | ==IHC== | ||
*p16 +ve -- stains most cells infected by HPV. | *[[p16]] +ve -- stains most cells infected by HPV. | ||
===Images=== | |||
<gallery> | |||
Image: High grade squamous intraepithelial lesion - 2 - p16 -- high mag.jpg | Block positive p16 staining in [[HSIL]]. (WC) | |||
Image:Consistent with HPV-associated SCC - p16 -- intermed mag.jpg | c/w [[Human papillomavirus-associated head and neck squamous cell carcinoma|HPV-assoc. SCC]] - p16 - intermed. mag. (WC/Nephron) | |||
Image:Consistent with HPV-associated SCC - p16 -- high mag.jpg | c/w HPV-assoc. SCC - p16 - high mag. (WC/Nephron) | |||
</gallery> | |||
==See also== | ==See also== | ||