Difference between revisions of "Uterine cervix"

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Uterine cervix (view source)

Revision as of 18:31, 17 November 2021

1,300 bytes removed ,  18:31, 17 November 2021
→‎Mesonephric adenocarcinoma
 
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==Mesonephric adenocarcinoma==
==Mesonephric adenocarcinoma==
===General===
{{Main|Mesonephric adenocarcinoma}}
*Arises from the [[mesonephric duct remnants]].
 
===Microscopic===
Features:<ref name=Ref_WMSP442>{{Ref WMSP|442}}</ref>
*Nuclear atypia - '''key feature'''.
**Nuclear crowding.
*Variable architecture:
**Tubular, papillary, solid, retiform (net-like<ref>URL: [http://www.thefreedictionary.com/retiform http://www.thefreedictionary.com/retiform]. Accessed on: 25 August 2012.</ref>).
 
DDx:
*[[Mesonephric duct remnants]].
*[[Cervical adenocarcinoma]].
*[[Colorectal adenocarcinoma]].
*Endometrioid adenocarcinoma.
 
===IHC===
Features:<ref name=Ref_WMSP442>{{Ref WMSP|442}}</ref>
*CK7 +ve.
*CD10 +ve.
*AMACR +ve.
*Napsin A +ve.<ref name=pmid31361605>{{cite journal |authors=Pors J, Segura S, Cheng A, Ji JX, Tessier-Cloutier B, Cochrane D, Fix DJ, Park K, Gilks B, Hoang L |title=Napsin-A and AMACR are Superior to HNF-1β in Distinguishing Between Mesonephric Carcinomas and Clear Cell Carcinomas of the Gynecologic Tract |journal=Appl Immunohistochem Mol Morphol |volume=28 |issue=8 |pages=593–601 |date=September 2020 |pmid=31361605 |pmc=6987010 |doi=10.1097/PAI.0000000000000801 |url=}}</ref>
*HNF-1beta +ve/-ve.
**Not useful for differentiation from clear cell carcinoma of the gynecologic tract.<ref name=pmid31361605/>
 
Others:<ref name=Ref_WMSP442>{{Ref WMSP|442}}</ref>
*[[CK20]] -ve.
*ER -ve.
*PR -ve.
*CEA -ve.


==Minimal deviation adenocarcinoma of the uterine cervix==
==Minimal deviation adenocarcinoma of the uterine cervix==
Michael
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