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Difference between revisions of "Lymph node metastasis"
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wikify link to nodal nevus
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| Micro = malignant cells foreign to the lymph node - typically subcapsular sinus; morphology dependent on specific cancer | | Micro = malignant cells foreign to the lymph node - typically subcapsular sinus; morphology dependent on specific cancer | ||
| Subtypes = dependent on primary tumour - macrometastasis, micrometastasis, isolated tumour cells | | Subtypes = dependent on primary tumour - macrometastasis, micrometastasis, isolated tumour cells | ||
| LMDDx = [[endometriosis]], ectopic [[decidua]], [[endosalpingiosis]], melanocytic nevus, [[dermatopathic lymphadenopathy]], [[sinus histiocytosis]], [[tumour deposit]] (dependent on site), pathology of the lymph node - see ''[[lymph node pathology]]'' and ''[[lymphoma]]'' | | LMDDx = [[endometriosis]], ectopic [[decidua]], [[endosalpingiosis]], [[nodal nevus|nodal (melanocytic) nevus]], [[dermatopathic lymphadenopathy]], [[sinus histiocytosis]], [[tumour deposit]] (dependent on site), pathology of the lymph node - see ''[[lymph node pathology]]'' and ''[[lymphoma]]'' | ||
| Stains = dependent on tumour | | Stains = dependent on tumour | ||
| IHC = dependent on tumour | | IHC = dependent on tumour | ||
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*Ectopic [[decidua]].<ref name=pmid15859655>{{Cite journal | last1 = Wu | first1 = DC. | last2 = Hirschowitz | first2 = S. | last3 = Natarajan | first3 = S. | title = Ectopic decidua of pelvic lymph nodes: a potential diagnostic pitfall. | journal = Arch Pathol Lab Med | volume = 129 | issue = 5 | pages = e117-20 | month = May | year = 2005 | doi = 10.1043/1543-2165(2005)129e117:EDOPLN2.0.CO;2 | PMID = 15859655 }}</ref> | *Ectopic [[decidua]].<ref name=pmid15859655>{{Cite journal | last1 = Wu | first1 = DC. | last2 = Hirschowitz | first2 = S. | last3 = Natarajan | first3 = S. | title = Ectopic decidua of pelvic lymph nodes: a potential diagnostic pitfall. | journal = Arch Pathol Lab Med | volume = 129 | issue = 5 | pages = e117-20 | month = May | year = 2005 | doi = 10.1043/1543-2165(2005)129e117:EDOPLN2.0.CO;2 | PMID = 15859655 }}</ref> | ||
*[[Endosalpingiosis]].<ref name=pmid20631604>{{Cite journal | last1 = Corben | first1 = AD. | last2 = Nehhozina | first2 = T. | last3 = Garg | first3 = K. | last4 = Vallejo | first4 = CE. | last5 = Brogi | first5 = E. | title = Endosalpingiosis in axillary lymph nodes: a possible pitfall in the staging of patients with breast carcinoma. | journal = Am J Surg Pathol | volume = 34 | issue = 8 | pages = 1211-6 | month = Aug | year = 2010 | doi = 10.1097/PAS.0b013e3181e5e03e | PMID = 20631604 }}</ref> | *[[Endosalpingiosis]].<ref name=pmid20631604>{{Cite journal | last1 = Corben | first1 = AD. | last2 = Nehhozina | first2 = T. | last3 = Garg | first3 = K. | last4 = Vallejo | first4 = CE. | last5 = Brogi | first5 = E. | title = Endosalpingiosis in axillary lymph nodes: a possible pitfall in the staging of patients with breast carcinoma. | journal = Am J Surg Pathol | volume = 34 | issue = 8 | pages = 1211-6 | month = Aug | year = 2010 | doi = 10.1097/PAS.0b013e3181e5e03e | PMID = 20631604 }}</ref> | ||
* | *[[Nodal nevus|Nodal (melanocytic) nevus]] - intracapsular or within the trabeculae.<ref name=pmid12717252>{{Cite journal | last1 = Biddle | first1 = DA. | last2 = Evans | first2 = HL. | last3 = Kemp | first3 = BL. | last4 = El-Naggar | first4 = AK. | last5 = Harvell | first5 = JD. | last6 = White | first6 = WL. | last7 = Iskandar | first7 = SS. | last8 = Prieto | first8 = VG. | title = Intraparenchymal nevus cell aggregates in lymph nodes: a possible diagnostic pitfall with malignant melanoma and carcinoma. | journal = Am J Surg Pathol | volume = 27 | issue = 5 | pages = 673-81 | month = May | year = 2003 | doi = | PMID = 12717252 }}</ref> | ||
**Incidence estimated at ~ 0.5% in axillary lymph nodes.<ref name=pmid8037154>{{cite journal |author=Bautista NC, Cohen S, Anders KH |title=Benign melanocytic nevus cells in axillary lymph nodes. A prospective incidence and immunohistochemical study with literature review |journal=Am. J. Clin. Pathol. |volume=102 |issue=1 |pages=102–8 |year=1994 |month=July |pmid=8037154 |doi= |url=}}</ref> | **Incidence estimated at ~ 0.5% in axillary lymph nodes.<ref name=pmid8037154>{{cite journal |author=Bautista NC, Cohen S, Anders KH |title=Benign melanocytic nevus cells in axillary lymph nodes. A prospective incidence and immunohistochemical study with literature review |journal=Am. J. Clin. Pathol. |volume=102 |issue=1 |pages=102–8 |year=1994 |month=July |pmid=8037154 |doi= |url=}}</ref> | ||
*[[Dermatopathic lymphadenopathy]].{{fact}} | *[[Dermatopathic lymphadenopathy]].{{fact}} | ||