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Difference between revisions of "Angiocentric glioma"
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==Molecular== | ==Molecular== | ||
* Deletion-truncation breakpoints in MYB/MYBL on 6q23-<ref>{{Cite journal | last1 = Ramkissoon | first1 = LA. | last2 = Horowitz | first2 = PM. | last3 = Craig | first3 = JM. | last4 = Ramkissoon | first4 = SH. | last5 = Rich | first5 = BE. | last6 = Schumacher | first6 = SE. | last7 = McKenna | first7 = A. | last8 = Lawrence | first8 = MS. | last9 = Bergthold | first9 = G. | title = Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1. | journal = Proc Natl Acad Sci U S A | volume = 110 | issue = 20 | pages = 8188-93 | month = May | year = 2013 | doi = 10.1073/pnas.1300252110 | PMID = 23633565 }}</ref> | * Deletion-truncation breakpoints in MYB/MYBL on 6q23-<ref>{{Cite journal | last1 = Ramkissoon | first1 = LA. | last2 = Horowitz | first2 = PM. | last3 = Craig | first3 = JM. | last4 = Ramkissoon | first4 = SH. | last5 = Rich | first5 = BE. | last6 = Schumacher | first6 = SE. | last7 = McKenna | first7 = A. | last8 = Lawrence | first8 = MS. | last9 = Bergthold | first9 = G. | title = Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1. | journal = Proc Natl Acad Sci U S A | volume = 110 | issue = 20 | pages = 8188-93 | month = May | year = 2013 | doi = 10.1073/pnas.1300252110 | PMID = 23633565 }}</ref> | ||
* MYB-QKI rearrangements <ref>{{Cite journal | last1 = Bandopadhayay | first1 = P. | last2 = Ramkissoon | first2 = LA. | last3 = Jain | first3 = P. | last4 = Bergthold | first4 = G. | last5 = Wala | first5 = J. | last6 = Zeid | first6 = R. | last7 = Schumacher | first7 = SE. | last8 = Urbanski | first8 = L. | last9 = O'Rourke | first9 = R. | title = MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. | journal = Nat Genet | volume = 48 | issue = 3 | pages = 273-82 | month = Mar | year = 2016 | doi = 10.1038/ng.3500 | PMID = 26829751 }}</ref> | |||
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Image:Neuropathology_case_V_07.jpg | Angiocentric glioma - MIB-1 immunostain (WC/jensflorian) | Image:Neuropathology_case_V_07.jpg | Angiocentric glioma - MIB-1 immunostain (WC/jensflorian) | ||
</gallery> | </gallery> | ||
==See also== | ==See also== | ||