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Difference between revisions of "Dysplasia-associated lesion or mass"
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Dysplasia-associated lesion or mass (view source)
Revision as of 13:49, 28 August 2018
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==General== | ==General== | ||
*Proving invasive malignancy (on histopathologic grounds alone) in the setting of chronic inflammation is difficult.<ref name=pmid7450425>{{Cite journal | last1 = Blackstone | first1 = MO. | last2 = Riddell | first2 = RH. | last3 = Rogers | first3 = BH. | last4 = Levin | first4 = B. | title = Dysplasia-associated lesion or mass (DALM) detected by colonoscopy in long-standing ulcerative colitis: an indication for colectomy. | journal = Gastroenterology | volume = 80 | issue = 2 | pages = 366-74 | month = Feb | year = 1981 | doi = | PMID = 7450425 }}</ref> | *Proving invasive malignancy (on histopathologic grounds alone) in the setting of chronic inflammation is difficult.<ref name=pmid7450425>{{Cite journal | last1 = Blackstone | first1 = MO. | last2 = Riddell | first2 = RH. | last3 = Rogers | first3 = BH. | last4 = Levin | first4 = B. | title = Dysplasia-associated lesion or mass (DALM) detected by colonoscopy in long-standing ulcerative colitis: an indication for colectomy. | journal = Gastroenterology | volume = 80 | issue = 2 | pages = 366-74 | month = Feb | year = 1981 | doi = | PMID = 7450425 }}</ref> | ||
* | *The diagnosis depended on correlation of endoscopy and histopathology - '''important'''.<ref name=pmid21912466>{{Cite journal | last1 = Neumann | first1 = H. | last2 = Vieth | first2 = M. | last3 = Langner | first3 = C. | last4 = Neurath | first4 = MF. | last5 = Mudter | first5 = J. | title = Cancer risk in IBD: how to diagnose and how to manage DALM and ALM. | journal = World J Gastroenterol | volume = 17 | issue = 27 | pages = 3184-91 | month = Jul | year = 2011 | doi = 10.3748/wjg.v17.i27.3184 | PMID = 21912466 }}</ref> | ||
**Biopsies are usually taken of the lesion and around the base. | **Biopsies are usually taken of the lesion and around the base. | ||
* | *This diagnosis (''DALM'') typically lead to [[colectomy]]. | ||
** | **The same histology today (2014) may be managed endoscopically.<ref name=pmid24975534>{{Cite journal | last1 = East | first1 = JE. | last2 = Toyonaga | first2 = T. | last3 = Suzuki | first3 = N. | title = Endoscopic management of nonpolypoid colorectal lesions in colonic IBD. | journal = Gastrointest Endosc Clin N Am | volume = 24 | issue = 3 | pages = 435-45 | month = Jul | year = 2014 | doi = 10.1016/j.giec.2014.03.003 | PMID = 24975534 }}</ref> | ||
</ref> | |||
==Gross== | ==Gross== | ||